Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT3 | P36888 | 5/20 | 0.70 |
| ▸ | IP6K2 | Q9UHH9 | 4/20 | 0.70 |
| ▸ | MKNK2 | Q9HBH9 | 4/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.68 |
| ▸ | MAPT | P10636 | 7/20 | 0.68 |
| ▸ | ABCB1 | P08183 | 7/20 | 0.68 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.68 |
| ▸ | MEN1 | O00255 | 6/20 | 0.68 |
| ▸ | MAOB | P27338 | 5/20 | 0.68 |
| ▸ | CYP1A1 | P04798 | 5/20 | 0.68 |
| ▸ | CYP1B1 | Q16678 | 5/20 | 0.68 |
| ▸ | CYP2C9 | P11712 | 5/20 | 0.68 |
| ▸ | CYP2C19 | P33261 | 5/20 | 0.68 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.68 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.68 |
| ▸ | NPC1 | O15118 | 4/20 | 0.68 |
| ▸ | HPGD | P15428 | 4/20 | 0.68 |
| ▸ | GABRP | O00591 | 4/20 | 0.68 |
| ▸ | GABRD | O14764 | 4/20 | 0.68 |
| ▸ | GABRA1 | P14867 | 4/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16977184 | 0.90 | MAOB (0.79) | FLT3IP6K2MKNK2KMT2AMAPT | |
| SCHEMBL19470002 | 0.90 | CYP1B1 (0.71) | FLT3IP6K2MKNK2KMT2AMAPT | |
| Genkwanin SCHEMBL866123 | 0.82 | FLT3 (1.00) | FLT3IP6K2MKNK2KMT2AMAPT | |
| Genkwanin SCHEMBL29445006 | 0.82 | FLT3 (1.00) | FLT3IP6K2MKNK2KMT2AMAPT | |
| Apigenin SCHEMBL5083245 | 0.82 | KMT2A (1.00) | FLT3IP6K2MKNK2KMT2AMAPT | |
| Apigenin SCHEMBL29351464 | 0.82 | KMT2A (1.00) | FLT3IP6K2MKNK2KMT2AMAPT | |
| Apigenin SCHEMBL19428 | 0.82 | KMT2A (1.00) | FLT3IP6K2MKNK2KMT2AMAPT | |
| SCHEMBL22084134 | 0.81 | MEN1 (0.70) | KMT2AMAPTABCB1CYP3A4MEN1 | |
| Apigenin SCHEMBL31477961 | 0.80 | KMT2A (0.97) | FLT3IP6K2MKNK2KMT2AMAPT | |
| Apigenin SCHEMBL31168790 | 0.80 | KMT2A (0.97) | FLT3IP6K2MKNK2KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10421768-B2 | Method of biotransformation of benzopyrone compounds into the corresponding phosphate-conjugated derivatives | NATIONAL TAIWAN UNIVERSITY (TW) | 2019-09-24 | — | — | US | disclosed |
| US-20170305944-A1 | METHOD OF BIOTRANSFORMATION OF BENZOPYRONE COMPOUNDS INTO THE CORRESPONDING PHOSPHATE-CONJUGATED DERIVATIVES | NATIONAL TAIWAN UNIVERSITY (TW) | 2017-10-26 | — | — | US | disclosed |
| US-20170305944-A1 | METHOD OF BIOTRANSFORMATION OF BENZOPYRONE COMPOUNDS INTO THE CORRESPONDING PHOSPHATE-CONJUGATED DERIVATIVES | NATIONAL TAIWAN UNIVERSITY (TW) | 2017-10-26 | — | — | US | disclosed |
| US-20170305944-A1 | METHOD OF BIOTRANSFORMATION OF BENZOPYRONE COMPOUNDS INTO THE CORRESPONDING PHOSPHATE-CONJUGATED DERIVATIVES | NATIONAL TAIWAN UNIVERSITY (TW) | 2017-10-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10421768-B2 | Method of biotransformation of benzopyrone compounds into the corresponding phosphate-conjugated derivatives | BPGM, PNKP, DHPS | FLT3 2069/4885IP6K2 1227/4885MKNK2 3837/4885 |
| US-20170305944-A1 | METHOD OF BIOTRANSFORMATION OF BENZOPYRONE COMPOUNDS INTO THE CORRESPONDING PHOSPHATE-CONJUGATED DERIVATIVES | BPGM, PNKP, DHPS | FLT3 2069/4885IP6K2 1227/4885MKNK2 3837/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.