Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | PIM1 | P11309 | 3/20 | 0.36 |
| ▸ | IRAK4 | Q9NWZ3 | 3/20 | 0.36 |
| ▸ | AAK1 | Q2M2I8 | 4/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | CDC7 | O00311 | 1/20 | 0.34 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.34 |
| ▸ | CDK2 | P24941 | 1/20 | 0.34 |
| ▸ | GSK3B | P49841 | 1/20 | 0.34 |
| ▸ | HIPK2 | Q9H2X6 | 1/20 | 0.34 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.34 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.34 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.34 |
| ▸ | CDK9 | P50750 | 1/20 | 0.34 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.34 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.34 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22084167 | 0.82 | MAPT (0.52) | MAPTCYP1A2CYP2C9PIM1IRAK4 | |
| SCHEMBL14882280 | 0.81 | PIM1 (0.42) | PIM1IRAK4AAK1MAP4K4DYRK3 | |
| SCHEMBL14881665 | 0.81 | PIM1 (0.42) | PIM1IRAK4AAK1MAP4K4DYRK3 | |
| SCHEMBL23408640 | 0.79 | PIM1 (0.40) | PIM1IRAK4AAK1DYRK3CCNT1 | |
| SCHEMBL21765939 | 0.78 | PDE10A (0.44) | PIM1IRAK4AAK1DYRK3CCNT1 | |
| SCHEMBL14881490 | 0.77 | IRAK4 (0.47) | PIM1IRAK4AAK1DYRK3CCNT1 | |
| SCHEMBL14881458 | 0.77 | IRAK4 (0.47) | PIM1IRAK4AAK1DYRK3CCNT1 | |
| SCHEMBL21765944 | 0.76 | IRAK4 (0.48) | PIM1IRAK4AAK1NTRK1 | |
| SCHEMBL21765966 | 0.76 | IRAK4 (0.46) | PIM1IRAK4AAK1DYRK3CCNT1 | |
| SCHEMBL18654925 | 0.76 | IRAK4 (0.48) | PIM1IRAK4AAK1NTRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020114465-A1 | PREPARATION AND APPLICATION OF HETEROAROMATIC IMINAZOLE COMPOUND | 上海轶诺药业有限公司 | 2020-06-11 | — | — | WO | disclosed |