SCHEMBL22084259 — predicted protein targets

Predicted protein targets (top 17)

	gene	UniProt	supporting neighbours	confidence
▸	CNR2	P34972	9/20	0.43

▸	NPSR1	Q6W5P4	2/20	0.39

▸	MAPT	P10636	2/20	0.39

▸	FPR1	P21462	1/20	0.35

▸	GAA	P10253	1/20	0.35

▸	MEN1	O00255	2/20	0.35

▸	KMT2A	Q03164	2/20	0.35

▸	HTT	P42858	1/20	0.34

▸	KDM4E	B2RXH2	2/20	0.34

▸	NPC1	O15118	1/20	0.34

▸	RAB9A	P51151	1/20	0.34

▸	HSD17B10	Q99714	1/20	0.34

▸	LMNA	P02545	2/20	0.34

▸	ALDH1A1	P00352	1/20	0.34

▸	HPGD	P15428	1/20	0.34

▸	PDE10A	Q9Y233	1/20	0.34

▸	L3MBTL1	Q9Y468	1/20	0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL22084944	0.84	NPSR1 (0.37)	NPSR1MAPTGAAMEN1KMT2A
SCHEMBL28449083	0.81	MAPT (0.40)	NPSR1MAPTGAAMEN1KMT2A
SCHEMBL28443373	0.77	NPSR1 (0.34)	NPSR1MAPTMEN1KMT2AHTT
SCHEMBL22041587	0.76	LMNA (0.43)	NPSR1MAPTGAAMEN1KMT2A
SCHEMBL29659631	0.76	LMNA (0.43)	NPSR1MAPTGAAMEN1KMT2A
SCHEMBL28443895	0.75	TP53 (0.41)	MAPTGAAMEN1KMT2AKDM4E
SCHEMBL28701449	0.75	SLC6A2 (0.35)	NPSR1MAPT
SCHEMBL22084262	0.74	KDM4E (0.37)	NPSR1MAPTGAAMEN1KMT2A
SCHEMBL22084951	0.73	KDM4E (0.40)	NPSR1MAPTGAAMEN1KMT2A
SCHEMBL28443773	0.73	HTT (0.34)	NPSR1MAPTGAAMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2020113554-A1	QUINOLINE DERIVATIVE AND PREPARATION METHOD AND APPLICATION THEREOF	东莞市东阳光农药研发有限公司	2020-06-11	—	—	WO	disclosed