Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | KDR | P35968 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 2/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.33 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | F2 | P00734 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | PRNP | P04156 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | CASP3 | P42574 | 1/20 | 0.32 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.32 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.32 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28449083 | 0.91 | MAPT (0.40) | NPSR1MAPTESR1ESR2ALDH1A1 | |
| SCHEMBL22084944 | 0.87 | NPSR1 (0.37) | NPSR1MAPTPDE10AALDH1A1HTT | |
| SCHEMBL28701449 | 0.86 | SLC6A2 (0.35) | NPSR1MAPTICAM1SELE | |
| SCHEMBL22966293 | 0.85 | PDGFRB (0.36) | NPSR1KDRMAPTESR1ESR2 | |
| SCHEMBL29659631 | 0.82 | LMNA (0.43) | NPSR1MAPTALDH1A1TP53LMNA | |
| SCHEMBL22041587 | 0.82 | LMNA (0.43) | NPSR1MAPTALDH1A1TP53LMNA | |
| SCHEMBL22966213 | 0.82 | F2 (0.36) | NPSR1KDRMAPTESR1ESR2 | |
| SCHEMBL15929951 | 0.80 | ALDH1A1 (0.45) | NPSR1KDRMAPTESR1ALDH1A1 | |
| SCHEMBL28443895 | 0.80 | TP53 (0.41) | KDRMAPTALDH1A1TP53LMNA | |
| SCHEMBL29814968 | 0.78 | PPARD (0.37) | NPSR1MAPTICAM1SELE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110452167-B | Quinoline derivatives, preparation method and application thereof | 东莞市东阳光农药研发有限公司 | 2020-08-21 | — | — | CN | disclosed |