Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 6/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
| ▸ | ERBB4 | Q15303 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | TSHR | P16473 | 4/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | CRHBP | P24387 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29659631 | 1.00 | LMNA (0.43) | LMNAMAPTALDH1A1KDM4ENPSR1 | |
| SCHEMBL22041591 | 0.85 | LMNA (0.40) | LMNAMAPTALDH1A1KDM4ENPSR1 | |
| SCHEMBL22084944 | 0.84 | NPSR1 (0.37) | LMNAMAPTALDH1A1KDM4ENPSR1 | |
| SCHEMBL28449083 | 0.83 | MAPT (0.40) | LMNAMAPTALDH1A1KDM4ENPSR1 | |
| SCHEMBL28443373 | 0.82 | NPSR1 (0.34) | LMNAMAPTALDH1A1NPSR1KMT2A | |
| SCHEMBL28701449 | 0.81 | SLC6A2 (0.35) | MAPTNPSR1 | |
| SCHEMBL30356307 | 0.76 | PDE10A (0.34) | ALDH1A1KDM4E | |
| SCHEMBL22085053 | 0.76 | GAPDH (0.38) | LMNAMAPTALDH1A1KDM4ENPSR1 | |
| SCHEMBL22084259 | 0.76 | CNR2 (0.43) | LMNAMAPTALDH1A1KDM4ENPSR1 | |
| SCHEMBL15929951 | 0.75 | ALDH1A1 (0.45) | LMNAMAPTALDH1A1KDM4ENPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111566088-B | Quinoline derivative and preparation method and application thereof | 东莞市东阳光农药研发有限公司 | 2022-07-08 | — | — | CN | disclosed |
| CN-111566088-A | Quinoline derivative and preparation method and application thereof | 东莞市东阳光农药研发有限公司 | 2020-08-21 | — | — | CN | disclosed |
| WO-2020113554-A1 | QUINOLINE DERIVATIVE AND PREPARATION METHOD AND APPLICATION THEREOF | 东莞市东阳光农药研发有限公司 | 2020-06-11 | — | — | WO | disclosed |
| WO-2020113554-A1 | QUINOLINE DERIVATIVE AND PREPARATION METHOD AND APPLICATION THEREOF | 东莞市东阳光农药研发有限公司 | 2020-06-11 | — | — | WO | disclosed |