Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DUT | P33316 | 9/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22085101 | 0.81 | DUT (0.36) | DUTPKM | |
| SCHEMBL22085372 | 0.68 | DUT (0.40) | DUTPKM | |
| SCHEMBL2800300 | 0.66 | DUT (0.59) | DUTHPGDCRBN | |
| SCHEMBL20333609 | 0.63 | PKM (0.51) | DUTPKMCRBN | |
| Ethylene SCHEMBL28028835 | 0.63 | DUT (0.56) | DUTHPGDCRBN | |
| SCHEMBL22084687 | 0.63 | HPGD (0.35) | HPGDMEN1KMT2A | |
| SCHEMBL22085116 | 0.63 | DUT (0.32) | DUTPKM | |
| SCHEMBL26043869 | 0.61 | DUT (0.49) | DUTPKMCRBN | |
| SCHEMBL22084413 | 0.61 | HPGD (0.38) | HPGDMEN1KMT2A | |
| SCHEMBL20334334 | 0.61 | MAPT (0.58) | DUTPKMHPGDMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020117938-A1 | PRODRUGS OF ANTI-CANCER AND ANTI-AUTOIMMUNE DISEASES THERAPEUTIC AGENTS, AND METHODS OF MAKING AND USE THEREOF | UNIVERSITY OF MARYLAND, BALTIMORE (US) | 2020-06-11 | — | — | WO | disclosed |