Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DUT | P33316 | 5/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22085372 | 0.67 | DUT (0.40) | DUTPKM | |
| SCHEMBL22084690 | 0.63 | DUT (0.37) | DUTPKM | |
| SCHEMBL22085101 | 0.62 | DUT (0.36) | DUTPKM | |
| SCHEMBL20333622 | 0.62 | LMNA (0.50) | DUTPKM | |
| SCHEMBL20333609 | 0.60 | PKM (0.51) | DUTPKM | |
| SCHEMBL20334334 | 0.60 | MAPT (0.58) | DUTPKM | |
| SCHEMBL23498276 | 0.59 | DUT (0.48) | DUTPKM | |
| SCHEMBL29777943 | 0.59 | L3MBTL1 (0.60) | DUTPKM | |
| SCHEMBL23513472 | 0.58 | ALDH1A1 (0.44) | DUTPKM | |
| SCHEMBL25370943 | 0.58 | ALDH1A1 (0.49) | DUTPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020117938-A1 | PRODRUGS OF ANTI-CANCER AND ANTI-AUTOIMMUNE DISEASES THERAPEUTIC AGENTS, AND METHODS OF MAKING AND USE THEREOF | UNIVERSITY OF MARYLAND, BALTIMORE (US) | 2020-06-11 | — | — | WO | disclosed |