Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 6/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 6/20 | 0.33 |
| ▸ | HDAC10 | Q969S8 | 6/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 6/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 6/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 4/20 | 0.33 |
| ▸ | HDAC7 | Q8WUI4 | 4/20 | 0.33 |
| ▸ | HDAC11 | Q96DB2 | 4/20 | 0.33 |
| ▸ | HDAC9 | Q9UKV0 | 4/20 | 0.33 |
| ▸ | HDAC5 | Q9UQL6 | 4/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | NAMPT | P43490 | 2/20 | 0.33 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22086952 | 0.90 | KMT2A (0.33) | OPRM1HRH3HDAC1HDAC2HDAC10 | |
| SCHEMBL22086953 | 0.89 | KCNH2 (0.36) | OPRM1HRH3HDAC1HDAC2HDAC10 | |
| SCHEMBL22085070 | 0.89 | KMT2A (0.33) | OPRM1HRH3HDAC1HDAC2HDAC10 | |
| SCHEMBL24755025 | 0.89 | OPRM1 (0.32) | OPRM1HRH3HDAC1HDAC2HDAC10 | |
| SCHEMBL22085068 | 0.89 | KCNH2 (0.33) | OPRM1HRH3ALDH1A1HDAC1HDAC2 | |
| SCHEMBL22085066 | 0.89 | KCNH2 (0.33) | OPRM1HRH3ALDH1A1HDAC1HDAC2 | |
| SCHEMBL24754700 | 0.80 | HRH3 (0.32) | OPRM1HRH3HDAC1HDAC2HDAC10 | |
| SCHEMBL24754926 | 0.80 | KCNH2 (0.37) | OPRM1HRH3KMT2APOLBNAMPT | |
| SCHEMBL22086468 | 0.79 | KCNH2 (0.34) | OPRM1HRH3ALDH1A1HDAC1HDAC2 | |
| SCHEMBL22085063 | 0.79 | CA2 (0.34) | OPRM1HRH3HDAC1HDAC2HDAC10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020115286-A2 | CELL-PERMEABLE FLUOROGENIC FLUOROPHORES | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e. V. (DE) | 2020-06-11 | — | — | WO | disclosed |