Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 12/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 10/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 9/20 | 0.40 |
| ▸ | MME | P08473 | 3/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.36 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.36 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15203049 | 1.00 | OPRM1 (0.40) | OPRM1OPRK1OPRD1MMETAAR1 | |
| SCHEMBL3287025 | 0.79 | MME (0.46) | OPRM1OPRK1OPRD1MMESLC1A3 | |
| SCHEMBL3287017 | 0.79 | MME (0.46) | OPRM1OPRK1OPRD1MMESLC1A3 | |
| SCHEMBL8249357 | 0.74 | CTSK (0.58) | MME | |
| SCHEMBL2920753 | 0.74 | TAAR1 (0.53) | TAAR1 | |
| SCHEMBL1970032 | 0.74 | TAAR1 (0.53) | TAAR1 | |
| SCHEMBL6852338 | 0.74 | TAAR1 (0.53) | TAAR1 | |
| SCHEMBL1696684 | 0.73 | SLC1A3 (0.45) | OPRM1OPRK1OPRD1MMETAAR1 | |
| SCHEMBL13599518 | 0.73 | CAPN1 (0.38) | — | |
| SCHEMBL13962958 | 0.73 | SLC1A3 (0.45) | OPRM1OPRK1OPRD1MMETAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2822572-B1 | PEPTIDOMIMETIC MACROCYCLES | AILERON THERAPEUTICS INC (US) | 2020-06-10 | — | — | EP | disclosed |