Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 3/20 | 0.53 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | TSHR | P16473 | 3/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | APP | P05067 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL350673 | 0.87 | AKR1C1 (0.55) | MAP4K4ALDH1A1AKR1C1TSHRCYP2C19 | |
| SCHEMBL16424490 | 0.86 | HDAC1 (0.53) | HDAC1MAP4K4ALDH1A1LMNATSHR | |
| SCHEMBL1627580 | 0.83 | AKR1C1 (0.68) | HDAC1ALDH1A1AKR1C1LMNATSHR | |
| SCHEMBL2817038 | 0.83 | AKR1C1 (0.68) | MAP4K4ALDH1A1AKR1C1LMNATSHR | |
| SCHEMBL13456896 | 0.83 | AKR1C1 (0.62) | MAP4K4ALDH1A1AKR1C1TSHRL3MBTL1 | |
| SCHEMBL15897259 | 0.82 | ALDH1A1 (0.49) | HDAC1MAP4K4ALDH1A1AKR1C1LMNA | |
| SCHEMBL196949 | 0.82 | POLB (0.56) | HDAC1MAP4K4ALDH1A1AKR1C1LMNA | |
| SCHEMBL16897539 | 0.82 | LMNA (0.60) | MAP4K4ALDH1A1AKR1C1LMNATSHR | |
| SCHEMBL166581 | 0.82 | APP (0.50) | HDAC1MAP4K4ALDH1A1AKR1C1LMNA | |
| SCHEMBL2325209 | 0.82 | HDAC1 (0.55) | HDAC1MAP4K4ALDH1A1AKR1C1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220073485-A1 | Functionalised Amine Derivatives as IL-17 Modulators | UCB BIOPHARMA SRL (SOCIETE A RESPONSABILITE LIMITEE) (BE) | 2022-03-10 | — | — | US | disclosed |
| EP-3894003-A1 | FUNCTIONALISED AMINE DERIVATIVES AS IL-17 MODULATORS | UCB Biopharma SRL (BE) | 2021-10-20 | — | — | EP | disclosed |
| CN-113260418-A | Functionalized amine derivatives as IL-17 modulators | UCB生物制药有限责任公司 | 2021-08-13 | — | — | CN | disclosed |
| WO-2020120141-A1 | FUNCTIONALISED AMINE DERIVATIVES AS IL-17 MODULATORS | UCB Biopharma SRL (BE) | 2020-06-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220073485-A1 | Functionalised Amine Derivatives as IL-17 Modulators | IL17A, IL15, IL2 | HDAC1 286/4885MAP4K4 1563/4885ALDH1A1 437/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.