Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGDS | O60760 | 1/20 | 0.56 |
| ▸ | ALKBH2 | Q6NS38 | 1/20 | 0.56 |
| ▸ | KEAP1 | Q14145 | 4/20 | 0.55 |
| ▸ | NFE2L2 | Q16236 | 4/20 | 0.55 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | HTR1A | P08908 | 1/20 | 0.48 |
| ▸ | HTR7 | P34969 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | EGLN1 | Q9GZT9 | 3/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.47 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25347365 | 0.87 | ALKBH2 (0.61) | HPGDSALKBH2KEAP1NFE2L2PTGDR2 | |
| SCHEMBL186625 | 0.87 | MEN1 (0.58) | HPGDSALKBH2KEAP1NFE2L2PTGDR2 | |
| SCHEMBL16799807 | 0.80 | KEAP1 (0.59) | HPGDSALKBH2KEAP1NFE2L2PTGDR2 | |
| SCHEMBL181969 | 0.79 | TDP1 (0.55) | HPGDSALKBH2PTGDR2MEN1KMT2A | |
| SCHEMBL27897955 | 0.78 | HPGDS (0.52) | HPGDSALKBH2PTGDR2MEN1KMT2A | |
| SCHEMBL629211 | 0.77 | TP53 (0.67) | KEAP1NFE2L2MEN1KMT2ANPC1 | |
| SCHEMBL8686215 | 0.77 | TP53 (0.67) | KEAP1NFE2L2MEN1KMT2ANPC1 | |
| SCHEMBL17125367 | 0.76 | MEN1 (0.60) | HPGDSALKBH2KEAP1NFE2L2MEN1 | |
| SCHEMBL7510493 | 0.74 | ALKBH2 (0.71) | HPGDSALKBH2KEAP1NFE2L2MEN1 | |
| SCHEMBL2860519 | 0.74 | ALKBH2 (0.71) | HPGDSALKBH2KEAP1NFE2L2PTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020123855-A1 | INHIBITOR COMPOUNDS FOR MALE CONTRACEPTION | UNIVERSITY OF WASHINGTON (US) | 2020-06-18 | — | — | WO | disclosed |