SCHEMBL22097096

SCHEMBL22097096

c1ccc(-c2cc(-c3ccccc3)cc(-c3cc(-c4ccc(-c5ccc6c(c5)c5ccccc5c5c6ccc6c7ccccc7n(-c7ccccc7)c65)cc4)nc(-c4cc(-c5ccccc5)cc(-c5ccccc5)c4)n3)c2)cc1

nearest known ligand 0.40

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 4/20 0.36
L3MBTL1 Q9Y468 2/20 0.36
ATM Q13315 1/20 0.36
KMT2A Q03164 5/20 0.35
MEN1 O00255 4/20 0.35
ALDH1A1 P00352 3/20 0.35
MAPT P10636 3/20 0.35
HPGD P15428 3/20 0.35
NTSR1 P30989 1/20 0.35
PTGER4 P35408 1/20 0.32
LMNA P02545 2/20 0.32
GLA P06280 1/20 0.32
KDR P35968 2/20 0.31
DHODH Q02127 1/20 0.31
IL1R1 P14778 1/20 0.30
ADORA2A P29274 1/20 0.30
ADORA1 P30542 1/20 0.30
RXFP1 Q9HBX9 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22097107 0.92 MEN1 (0.40) KDM4EL3MBTL1ATMKMT2AMEN1
SCHEMBL22097192 0.92 MEN1 (0.40) KDM4EL3MBTL1ATMKMT2AMEN1
SCHEMBL22097265 0.92 KDM4E (0.41) KDM4EL3MBTL1ATMKMT2AMEN1
SCHEMBL22096971 0.91 KMT2A (0.40) KDM4EL3MBTL1ATMKMT2AMEN1
SCHEMBL22097057 0.91 KMT2A (0.40) KDM4EL3MBTL1ATMKMT2AMEN1
SCHEMBL22097118 0.89 MAPT (0.37) KDM4EL3MBTL1ATMKMT2AMEN1
SCHEMBL22097262 0.86 L3MBTL1 (0.41) KDM4EL3MBTL1ATMKMT2AMEN1
SCHEMBL21370232 0.86 MEN1 (0.39) KDM4EL3MBTL1ATMKMT2AMEN1
SCHEMBL22097203 0.86 L3MBTL1 (0.41) KDM4EL3MBTL1ATMKMT2AMEN1
SCHEMBL16904468 0.85 KDM4E (0.44) KDM4EL3MBTL1ATMKMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11236075-B2 Organic compound and organic electroluminescence device using the same LUMINESCENCE TECHNOLOGY CORP. (TW) 2022-02-01 US disclosed
US-20200190065-A1 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME LUMINESCENCE TECHNOLOGY CORPORATION (TW) 2020-06-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11236075-B2 Organic compound and organic electroluminescence device using the same ICMT, OR10J3, PIEZO1 KDM4E 1846/4885L3MBTL1 179/4885ATM 3884/4885
US-20200190065-A1 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME ICMT, OR10J3, PIEZO1 KDM4E 1846/4885L3MBTL1 179/4885ATM 3884/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.