SCHEMBL22097150

SCHEMBL22097150

c1ccc(-c2nc(-c3ccc(-c4ccccn4)cc3)nc(-c3ccc4c(c3)c3ccccc3c3c4ccc4c5ccccc5n(-c5ccccc5)c43)n2)cc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DHODH Q02127 1/20 0.36
L3MBTL1 Q9Y468 2/20 0.35
KDM4E B2RXH2 2/20 0.35
ATM Q13315 1/20 0.35
MCL1 Q07820 3/20 0.34
TSHR P16473 3/20 0.34
HSD17B10 Q99714 2/20 0.34
MAPK1 P28482 1/20 0.34
MAPT P10636 5/20 0.34
KMT2A Q03164 3/20 0.34
PPP1CA P62136 2/20 0.34
NPSR1 Q6W5P4 2/20 0.34
CYP2C19 P33261 2/20 0.34
CYP1A2 P05177 1/20 0.34
CYP2C9 P11712 1/20 0.34
NPY5R Q15761 1/20 0.34
ALDH1A1 P00352 3/20 0.33
HPGD P15428 2/20 0.33
GRM5 P41594 1/20 0.33
MEN1 O00255 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22097130 0.97 GRM5 (0.37) DHODHL3MBTL1KDM4EATMMCL1
SCHEMBL22097250 0.95 DHODH (0.38) DHODHL3MBTL1KDM4EATMMCL1
SCHEMBL22097074 0.90 L3MBTL1 (0.42) L3MBTL1KDM4EATMMAPTKMT2A
SCHEMBL22097075 0.90 L3MBTL1 (0.42) L3MBTL1KDM4EATMMAPTKMT2A
SCHEMBL22097203 0.89 L3MBTL1 (0.41) L3MBTL1KDM4EATMMAPTKMT2A
SCHEMBL22097262 0.89 L3MBTL1 (0.41) L3MBTL1KDM4EATMMAPTKMT2A
SCHEMBL22097265 0.88 KDM4E (0.41) L3MBTL1KDM4EATMMAPTKMT2A
SCHEMBL22096987 0.88 DHODH (0.36) DHODHL3MBTL1KDM4EATMTSHR
SCHEMBL22096971 0.87 KMT2A (0.40) L3MBTL1KDM4EATMMAPTKMT2A
SCHEMBL22097057 0.87 KMT2A (0.40) L3MBTL1KDM4EATMMAPTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11236075-B2 Organic compound and organic electroluminescence device using the same LUMINESCENCE TECHNOLOGY CORP. (TW) 2022-02-01 US disclosed
US-20200190065-A1 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME LUMINESCENCE TECHNOLOGY CORPORATION (TW) 2020-06-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11236075-B2 Organic compound and organic electroluminescence device using the same ICMT, OR10J3, PIEZO1 DHODH 583/4885L3MBTL1 179/4885KDM4E 1846/4885
US-20200190065-A1 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME ICMT, OR10J3, PIEZO1 DHODH 583/4885L3MBTL1 179/4885KDM4E 1846/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.