Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 1/20 | 0.48 |
| ▸ | CES2 | O00748 | 3/20 | 0.47 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.41 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | FAAH | O00519 | 6/20 | 0.39 |
| ▸ | CES1 | P23141 | 4/20 | 0.39 |
| ▸ | LPAR3 | Q9UBY5 | 3/20 | 0.39 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.39 |
| ▸ | LPAR2 | Q9HBW0 | 2/20 | 0.39 |
| ▸ | DGKA | P23743 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20156712 | 0.83 | CYP4F2 (0.36) | CYP4F2CYP4A11 | |
| SCHEMBL19820208 | 0.82 | GPR84 (0.48) | CES2TSHRMEN1CYP1A2KMT2A | |
| SCHEMBL2785037 | 0.82 | NAAA (0.45) | NAAACES2EPHX1CYP4F2CYP4A11 | |
| SCHEMBL11240792 | 0.82 | NAAA (0.45) | NAAACES2EPHX1CYP4F2CYP4A11 | |
| SCHEMBL20915214 | 0.82 | NAAA (0.45) | NAAACES2EPHX1CYP4F2CYP4A11 | |
| SCHEMBL20936508 | 0.82 | NAAA (0.45) | NAAACES2EPHX1CYP4F2CYP4A11 | |
| SCHEMBL20936457 | 0.82 | NAAA (0.45) | NAAACES2EPHX1CYP4F2CYP4A11 | |
| SCHEMBL20915341 | 0.82 | NAAA (0.45) | NAAACES2EPHX1CYP4F2CYP4A11 | |
| SCHEMBL18377022 | 0.80 | GPR84 (0.57) | TSHRMEN1CYP1A2KMT2AHSD17B10 | |
| SCHEMBL13975763 | 0.80 | FAAH (0.46) | CES2TSHRFAAHCES1DGKA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3666766-A1 | PYRIDINE COMPOUND SUBSTITUTED WITH AZOLE | Taisho Pharmaceutical Co., Ltd. (JP) | 2020-06-17 | — | — | EP | disclosed |