Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.54 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.51 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.51 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.50 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17742175 | 0.85 | HPGD (0.55) | HPGDKMT2AGAA | |
| SCHEMBL6360887 | 0.83 | HPGD (0.79) | HPGDKMT2AGAAKDM4ELMNA | |
| SCHEMBL14233695 | 0.82 | HPGD (0.54) | HPGDGAAMTNR1AMTNR1BALDH1A1 | |
| SCHEMBL16015432 | 0.82 | MAPT (0.48) | HPGDGAAMTNR1AMTNR1BCYP4F2 | |
| SCHEMBL21659171 | 0.80 | ERCC1 (0.65) | HPGDKMT2AGAAALDH1A1MEN1 | |
| SCHEMBL14233715 | 0.78 | MAPT (0.44) | HPGDKMT2AGAAMTNR1AMTNR1B | |
| SCHEMBL10029412 | 0.78 | MAPT (0.70) | HPGDKMT2AKDM4ELMNAALDH1A1 | |
| SCHEMBL12303899 | 0.77 | PRMT6 (0.51) | HPGDKMT2AGAAKDM4ELMNA | |
| SCHEMBL10750775 | 0.76 | ALDH1A1 (0.62) | HPGDMTNR1AMTNR1BCYP4F2CYP4A11 | |
| SCHEMBL3674500 | 0.76 | KEAP1 (0.61) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3666766-A1 | PYRIDINE COMPOUND SUBSTITUTED WITH AZOLE | Taisho Pharmaceutical Co., Ltd. (JP) | 2020-06-17 | — | — | EP | disclosed |