Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLG | P00747 | 3/20 | 0.37 |
| ▸ | PLAU | P00749 | 3/20 | 0.37 |
| ▸ | KLK1 | P06870 | 2/20 | 0.35 |
| ▸ | KLK6 | Q92876 | 2/20 | 0.35 |
| ▸ | F2R | P25116 | 1/20 | 0.34 |
| ▸ | PNLIP | P16233 | 1/20 | 0.34 |
| ▸ | F10 | P00742 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.32 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.31 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20764545 | 0.84 | STAT3 (0.39) | PLGPLAUF2RPNLIPSLC6A3 | |
| SCHEMBL20764507 | 0.65 | STAT3 (0.45) | PLGPLAUKLK1KLK6PNLIP | |
| SCHEMBL15290168 | 0.59 | F2R (0.59) | F2RPNLIPPOLB | |
| SCHEMBL22099993 | 0.59 | MAPT (0.37) | PLGPLAUNR1H4POLBGLA | |
| SCHEMBL15290169 | 0.59 | NPC1 (0.60) | F2RPNLIPPOLB | |
| SCHEMBL16329191 | 0.58 | CYP17A1 (0.46) | — | |
| SCHEMBL23097214 | 0.58 | CA1 (0.43) | POLB | |
| SCHEMBL16883314 | 0.58 | F2R (0.46) | F2RPOLB | |
| SCHEMBL21579491 | 0.57 | TERT (0.64) | PLGPLAUKLK1KLK6PNLIP | |
| SCHEMBL15290179 | 0.57 | NPC1 (0.59) | F2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11034648-B2 | Cystobactamide derivatives | HELMHOLTZ-ZENTRUM FÜR (DE) | 2021-06-15 | — | — | US | disclosed |
| US-20200190020-A1 | NOVEL CYSTOBACTAMIDE DERIVATIVES | Helmholtz-Zentrum für Infektionsforschung GmbH (DE) | 2020-06-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11034648-B2 | Cystobactamide derivatives | CTH, CBS, SLC7A11 | PLG 2048/4885PLAU 1564/4885KLK1 1623/4885 |
| US-20200190020-A1 | NOVEL CYSTOBACTAMIDE DERIVATIVES | CTH, CBS, SLC7A11 | PLG 2688/4885PLAU 2260/4885KLK1 1592/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.