SCHEMBL22099990

SCHEMBL22099990

Cc1cc2c3ccccc3n(-c3ccccc3)c2cn1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.58
L3MBTL1 Q9Y468 2/20 0.58
ATM Q13315 1/20 0.58
MAPK1 P28482 2/20 0.40
HTT P42858 1/20 0.40
CYP1A2 P05177 2/20 0.38
CYP2A6 P11509 1/20 0.38
MAPK8 P45983 1/20 0.38
MEN1 O00255 2/20 0.38
ALDH1A1 P00352 2/20 0.38
TSHR P16473 2/20 0.38
KMT2A Q03164 2/20 0.38
HSD17B10 Q99714 2/20 0.38
HPGD P15428 1/20 0.38
CASP1 P29466 1/20 0.38
CASP7 P55210 1/20 0.38
AHR P35869 1/20 0.38
PGR P06401 1/20 0.37
PLA2G2A P14555 1/20 0.36
HKDC1 Q2TB90 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20751994 0.87 KDM4E (0.58) KDM4EL3MBTL1ATMMAPK1HTT
SCHEMBL21321848 0.81 ATM (0.50) KDM4EL3MBTL1ATMMAPK1HTT
SCHEMBL3337353 0.78 GPR3 (0.57) KDM4EL3MBTL1HTTCYP1A2CYP2A6
SCHEMBL19149349 0.77 L3MBTL1 (0.53) KDM4EL3MBTL1ATMHTTCYP1A2
SCHEMBL18958783 0.77 L3MBTL1 (0.53) KDM4EL3MBTL1ATMHTTMEN1
SCHEMBL21085499 0.77 KDM4E (0.49) KDM4EL3MBTL1ATMCYP1A2MAPK8
SCHEMBL27426967 0.77 L3MBTL1 (0.82) KDM4EL3MBTL1ATMMAPK1HTT
SCHEMBL1638441 0.77 L3MBTL1 (0.82) KDM4EL3MBTL1ATMMAPK1HTT
SCHEMBL31962 0.76 L3MBTL1 (1.00) KDM4EL3MBTL1ATMMAPK1HTT
Benzene SCHEMBL28486033 0.76 L3MBTL1 (1.00) KDM4EL3MBTL1ATMMAPK1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11834459-B2 Host materials for electroluminescent devices UNIVERSAL DISPLAY CORPORATION (US) 2023-12-05 US disclosed
US-11834459-B2 Host materials for electroluminescent devices UNIVERSAL DISPLAY CORPORATION (US) 2023-12-05 US disclosed
US-20230389413-A1 Organic Electroluminescent Materials and Devices UNIVERSAL DISPLAY CORPORATION 2023-11-30 US disclosed
US-20230389413-A1 Organic Electroluminescent Materials and Devices UNIVERSAL DISPLAY CORPORATION 2023-11-30 US disclosed
US-11758807-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION 2023-09-12 US disclosed
US-11758807-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION 2023-09-12 US disclosed
US-20210367162-A1 HETEROCYCLIC COMPOUND AND LIGHT-EMITTING DEVICE INCLUDING SAME SAMSUNG DISPLAY CO., LTD. (KR) 2021-11-25 US disclosed
US-20200274081-A1 Organic Electroluminescent Materials and Devices UNIVERSAL DISPLAY CORPORATION 2020-08-27 US disclosed
US-20200190103-A1 HOST MATERIALS FOR ELECTROLUMINESCENT DEVICES UNIVERSAL DISPLAY CORPORATION 2020-06-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230389413-A1 Organic Electroluminescent Materials and Devices GLRA3, ESRRG, GLRA1 KDM4E 2665/4885L3MBTL1 1754/4885ATM 3936/4885
US-20200274081-A1 Organic Electroluminescent Materials and Devices GLRA3, ESRRG, GLRA1 KDM4E 2665/4885L3MBTL1 1754/4885ATM 3936/4885
US-20200190103-A1 HOST MATERIALS FOR ELECTROLUMINESCENT DEVICES RPS4X, MLX, RPS4Y1 KDM4E 1801/4885L3MBTL1 2433/4885ATM 2153/4885
US-11834459-B2 Host materials for electroluminescent devices RPS4X, MLX, RPS4Y1 KDM4E 1801/4885L3MBTL1 2433/4885ATM 2153/4885
US-11758807-B2 Organic electroluminescent materials and devices GLRA3, ESRRG, GLRA1 KDM4E 2665/4885L3MBTL1 1754/4885ATM 3936/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.