Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 12/20 | 0.75 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | BCHE | P06276 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.44 |
| ▸ | RELA | Q04206 | 1/20 | 0.44 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10270947 | 0.86 | TRPM8 (1.00) | TRPM8ALDH1A1BCHECYP3A4NFKB1 | |
| SCHEMBL18537071 | 0.79 | TRPM8 (0.88) | TRPM8ALDH1A1MAPTBCHECYP3A4 | |
| SCHEMBL22100701 | 0.74 | TRPM8 (0.75) | TRPM8ALDH1A1MAPTBCHECYP3A4 | |
| SCHEMBL10270949 | 0.72 | TRPM8 (1.00) | TRPM8ALDH1A1MAPTKDM4EPOLB | |
| SCHEMBL30532223 | 0.72 | TRPM8 (1.00) | TRPM8ALDH1A1MAPTKDM4EPOLB | |
| SCHEMBL13277569 | 0.72 | TRPM8 (1.00) | TRPM8ALDH1A1THRBATM | |
| SCHEMBL10270778 | 0.72 | TRPM8 (1.00) | TRPM8ALDH1A1THRBATM | |
| SCHEMBL22100706 | 0.72 | TRPM8 (0.73) | TRPM8ALDH1A1BCHECYP3A4NFKB1 | |
| SCHEMBL22100712 | 0.72 | TRPM8 (0.82) | TRPM8ALDH1A1MAPTKDM4EPOLB | |
| SCHEMBL1699151 | 0.71 | TRPM8 (1.00) | TRPM8ALDH1A1MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2501761-B1 | USE OF PHYSIOLOGICAL COOLING ACTIVE INGREDIENTS, AND AGENTS CONTAINING SUCH ACTIVE INGREDIENTS | SYMRISE AG (DE) | 2020-06-17 | — | — | EP | disclosed |