Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 6/20 | 0.73 |
| ▸ | BCHE | P06276 | 2/20 | 0.51 |
| ▸ | SNCA | P37840 | 1/20 | 0.51 |
| ▸ | ACHE | P22303 | 1/20 | 0.51 |
| ▸ | RNF4 | P78317 | 1/20 | 0.48 |
| ▸ | G6PC1 | P35575 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.47 |
| ▸ | RELA | Q04206 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | GSK3B | P49841 | 1/20 | 0.46 |
| ▸ | BACE1 | P56817 | 1/20 | 0.46 |
| ▸ | PLAAT3 | P53816 | 1/20 | 0.46 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22100701 | 0.85 | TRPM8 (0.75) | TRPM8BCHEMAOBCYP3A4NFKB1 | |
| SCHEMBL10270952 | 0.85 | TRPM8 (1.00) | TRPM8BCHESNCAACHERNF4 | |
| SCHEMBL18536909 | 0.74 | TRPM8 (0.83) | TRPM8BCHESNCAMAOBCYP3A4 | |
| SCHEMBL10270945 | 0.73 | TRPM8 (1.00) | TRPM8BCHESNCAMAOBCYP3A4 | |
| SCHEMBL10922363 | 0.72 | RNF4 (0.69) | TRPM8ACHERNF4MEN1KMT2A | |
| SCHEMBL8614182 | 0.72 | MAOB (0.69) | TRPM8BCHEMAOBCYP3A4NFKB1 | |
| SCHEMBL22100703 | 0.72 | TRPM8 (0.75) | TRPM8BCHECYP3A4NFKB1NFKB2 | |
| SCHEMBL22100767 | 0.71 | TRPM8 (0.53) | TRPM8MAOBMEN1KMT2ALMNA | |
| SCHEMBL20777273 | 0.71 | TRPM8 (0.77) | TRPM8BCHESNCAMAOBCYP3A4 | |
| SCHEMBL29779967 | 0.71 | TRPM8 (0.77) | TRPM8BCHESNCAMAOBCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2501761-B1 | USE OF PHYSIOLOGICAL COOLING ACTIVE INGREDIENTS, AND AGENTS CONTAINING SUCH ACTIVE INGREDIENTS | SYMRISE AG (DE) | 2020-06-17 | — | — | EP | disclosed |