Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 4/20 | 0.54 |
| ▸ | NFE2L2 | Q16236 | 5/20 | 0.42 |
| ▸ | PTGER3 | P43115 | 4/20 | 0.36 |
| ▸ | PTGER2 | P43116 | 4/20 | 0.36 |
| ▸ | PTGER4 | P35408 | 3/20 | 0.36 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.36 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.36 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.35 |
| ▸ | TFEB | P19484 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | BCHE | P06276 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19123945 | 0.72 | NFE2L2 (0.44) | NFE2L2CYP1A1CYP1A2MAPT | |
| SCHEMBL15427433 | 0.72 | NFE2L2 (0.44) | NFE2L2CYP1A1CYP1A2MAPT | |
| SCHEMBL10271038 | 0.70 | TRPM8 (1.00) | TRPM8NFE2L2CYP1A1CYP1A2CYP2D6 | |
| SCHEMBL16955328 | 0.70 | CA1 (0.44) | NFE2L2CYP1A1CYP1A2MAPTLMNA | |
| SCHEMBL14999526 | 0.70 | CA1 (0.41) | NFE2L2CYP1A1CYP1A2MAPTLMNA | |
| SCHEMBL7102162 | 0.68 | CA1 (0.59) | NFE2L2CYP1A2NPC1LMNARAB9A | |
| SCHEMBL22002870 | 0.67 | NPSR1 (0.38) | TRPM8MAPTNPC1RAB9AMEN1 | |
| SCHEMBL30242804 | 0.67 | APP (0.50) | NFE2L2MAPTLMNAMEN1ALDH1A1 | |
| SCHEMBL27605144 | 0.66 | TRPM8 (0.61) | TRPM8CYP1A2CYP2D6MAPTNPC1 | |
| SCHEMBL16253604 | 0.66 | CA1 (0.38) | NFE2L2CYP1A1CYP1A2LMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2501761-B1 | USE OF PHYSIOLOGICAL COOLING ACTIVE INGREDIENTS, AND AGENTS CONTAINING SUCH ACTIVE INGREDIENTS | SYMRISE AG (DE) | 2020-06-17 | — | — | EP | disclosed |