Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | TRPM8 | Q7Z2W7 | 7/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22100710 | 0.84 | TRPM8 (0.60) | NPC1ALDH1A1TRPM8SMN1; SMN2LMNA | |
| SCHEMBL22100829 | 0.81 | TRPM8 (0.60) | NPC1ALDH1A1TRPM8SMN1; SMN2LMNA | |
| SCHEMBL10914231 | 0.72 | NPC1 (0.66) | NPC1ALDH1A1TRPM8SMN1; SMN2LMNA | |
| SCHEMBL14821822 | 0.70 | ALDH1A1 (0.59) | NPC1ALDH1A1TRPM8SMN1; SMN2LMNA | |
| SCHEMBL10271046 | 0.69 | TRPM8 (1.00) | NPC1ALDH1A1TRPM8SMN1; SMN2LMNA | |
| SCHEMBL14822030 | 0.69 | ALDH1A1 (0.52) | NPC1ALDH1A1TRPM8SMN1; SMN2LMNA | |
| SCHEMBL14822029 | 0.69 | ALDH1A1 (0.55) | NPC1ALDH1A1TRPM8SMN1; SMN2LMNA | |
| SCHEMBL16135774 | 0.69 | ALDH1A1 (0.68) | NPC1ALDH1A1TRPM8LMNAHTT | |
| SCHEMBL22100766 | 0.69 | TRPM8 (0.55) | NPC1ALDH1A1TRPM8SMN1; SMN2LMNA | |
| SCHEMBL14821559 | 0.68 | NPC1 (0.55) | NPC1ALDH1A1TRPM8SMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2501761-B1 | USE OF PHYSIOLOGICAL COOLING ACTIVE INGREDIENTS, AND AGENTS CONTAINING SUCH ACTIVE INGREDIENTS | SYMRISE AG (DE) | 2020-06-17 | — | — | EP | disclosed |