Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR2 | P25025 | 2/20 | 0.38 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.37 |
| ▸ | MAT2A | P31153 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.33 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | PKM | P14618 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22101725 | 0.85 | GRIN1 (0.40) | CXCR2KDM5BMAT2AMAPTPOLB | |
| SCHEMBL22393919 | 0.84 | KDM5B (0.36) | CXCR2KDM5BMAT2AMAPTPOLB | |
| SCHEMBL22101411 | 0.84 | KDM5B (0.36) | CXCR2KDM5BMAT2AMAPTPOLB | |
| SCHEMBL22393704 | 0.81 | MAPT (0.36) | CXCR2KDM5BMAT2AMAPTPOLB | |
| SCHEMBL22101447 | 0.73 | BCAT2 (0.33) | CXCR2MAT2ABCAT2BCAT1 | |
| SCHEMBL22101360 | 0.73 | MAPT (0.35) | CXCR2MAT2AMAPTPOLBTP53 | |
| SCHEMBL22101696 | 0.72 | KDM5B (0.39) | KDM5BMAT2AMAPTPOLBL3MBTL1 | |
| SCHEMBL22101695 | 0.70 | MAPT (0.40) | KDM5BMAT2AMAPTPOLBL3MBTL1 | |
| SCHEMBL22101427 | 0.70 | PABPC1 (0.42) | KDM5BMAT2AMAPTL3MBTL1TSHR | |
| SCHEMBL22101884 | 0.69 | MAPT (0.37) | KDM5BMAT2AMAPTPOLBL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3666772-A1 | DIARYLTHIOHYDANTOIN COMPOUND AS ANDROGEN RECEPTOR ANTAGONIST | Chia Tai Tianqing Pharmaceutical Group Co., Ltd. (CN) | 2020-06-17 | — | — | EP | disclosed |