Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.39 |
| ▸ | MAT2A | P31153 | 1/20 | 0.38 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.38 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 5/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | NOS3 | P29474 | 1/20 | 0.36 |
| ▸ | NOS2 | P35228 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22101725 | 0.84 | GRIN1 (0.40) | KDM5BMAT2AGRIN1GRIN2AL3MBTL1 | |
| SCHEMBL22101695 | 0.84 | MAPT (0.40) | KDM5BMAT2AGRIN1GRIN2AL3MBTL1 | |
| SCHEMBL22101427 | 0.84 | PABPC1 (0.42) | KDM5BMAT2AL3MBTL1PKMKDM4E | |
| SCHEMBL22393765 | 0.83 | MAPT (0.40) | KDM5BMAT2AL3MBTL1PKMKDM4E | |
| SCHEMBL13759891 | 0.77 | PIK3CB (0.36) | KDM4EALDH1A1MAPTSMN1; SMN2NPC1 | |
| SCHEMBL13759892 | 0.77 | KDM4E (0.36) | L3MBTL1KDM4EALDH1A1MAPTPIK3CD | |
| SCHEMBL13833755 | 0.76 | PKM (0.58) | PKMKDM4EALDH1A1MAPTPOLB | |
| SCHEMBL22101440 | 0.75 | POLB (0.33) | KDM5BMAT2AL3MBTL1PKMTSHR | |
| SCHEMBL17298042 | 0.74 | GRIN1 (0.62) | GRIN1GRIN2APKMKDM4EALDH1A1 | |
| SCHEMBL22423478 | 0.72 | HEXA (0.34) | KDM4EALDH1A1NOS3NOS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3666772-A1 | DIARYLTHIOHYDANTOIN COMPOUND AS ANDROGEN RECEPTOR ANTAGONIST | Chia Tai Tianqing Pharmaceutical Group Co., Ltd. (CN) | 2020-06-17 | — | — | EP | disclosed |