Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.35 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.33 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.33 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.32 |
| ▸ | PDE5A | O76074 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22101539 | 0.85 | FFAR4 (0.35) | MAPTRXFP1KDM4EALDH1A1PIK3CB | |
| SCHEMBL22101536 | 0.85 | THRB (0.38) | MAPTRXFP1KDM4EALDH1A1PIK3CB | |
| SCHEMBL22101868 | 0.85 | KDM4E (0.35) | MAPTRXFP1KDM4EADORA2AADORA1 | |
| SCHEMBL22101540 | 0.84 | CYP2C9 (0.35) | RXFP1KDM4EALDH1A1PIK3CBGRIN1 | |
| SCHEMBL24425379 | 0.83 | MAPT (0.34) | MAPTALDH1A1ADORA2AADORA1TP53 | |
| SCHEMBL22393590 | 0.83 | ELANE (0.32) | ADORA2AADORA1 | |
| SCHEMBL22101725 | 0.78 | GRIN1 (0.40) | MAPTRXFP1KDM4EALDH1A1GRIN1 | |
| SCHEMBL22101452 | 0.75 | MAPT (0.33) | MAPTPIK3CBPDE5A | |
| SCHEMBL22101522 | 0.72 | PIK3CB (0.37) | PIK3CB | |
| SCHEMBL22101709 | 0.71 | GRIN1 (0.32) | RXFP1KDM4EALDH1A1GRIN1GRIN2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3666772-A1 | DIARYLTHIOHYDANTOIN COMPOUND AS ANDROGEN RECEPTOR ANTAGONIST | Chia Tai Tianqing Pharmaceutical Group Co., Ltd. (CN) | 2020-06-17 | — | — | EP | disclosed |