Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | MAT2A | P31153 | 1/20 | 0.31 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.31 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.30 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22101430 | 0.82 | MAPT (0.38) | POLBMAT2AMAPTKCNH2RXFP1 | |
| SCHEMBL22101503 | 0.81 | L3MBTL1 (0.36) | POLBL3MBTL1MAPTRXFP1NTRK1 | |
| SCHEMBL22393765 | 0.77 | MAPT (0.40) | POLBL3MBTL1MAT2AKDM5BMAPT | |
| SCHEMBL22101696 | 0.75 | KDM5B (0.39) | POLBL3MBTL1MAT2AKDM5BMAPT | |
| SCHEMBL22101427 | 0.72 | PABPC1 (0.42) | L3MBTL1MAT2AKDM5BMAPTRXFP1 | |
| SCHEMBL22101360 | 0.70 | MAPT (0.35) | POLBMAT2AMAPTRXFP1ACKR3 | |
| SCHEMBL22101447 | 0.70 | BCAT2 (0.33) | MAT2A | |
| SCHEMBL22101896 | 0.70 | MAPT (0.40) | POLBMAT2AMAPTNTRK1NTRK2 | |
| SCHEMBL13833755 | 0.66 | PKM (0.58) | POLBMAPTRXFP1NTRK1NTRK2 | |
| SCHEMBL22101695 | 0.65 | MAPT (0.40) | POLBL3MBTL1MAT2AKDM5BMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3666772-A1 | DIARYLTHIOHYDANTOIN COMPOUND AS ANDROGEN RECEPTOR ANTAGONIST | Chia Tai Tianqing Pharmaceutical Group Co., Ltd. (CN) | 2020-06-17 | — | — | EP | disclosed |