Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | BRAF | P15056 | 5/20 | 0.49 |
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | APP | P05067 | 1/20 | 0.47 |
| ▸ | SNCA | P37840 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | HTT | P42858 | 3/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20269250 | 0.92 | CYP3A4 (0.57) | CYP3A4TSHRBRAFMAPTALOX15 | |
| SCHEMBL11475061 | 0.86 | CYP3A4 (0.70) | CYP3A4TSHRBRAFMAPTKDM4E | |
| SCHEMBL20285584 | 0.84 | MAPT (0.51) | CYP3A4MAPTKDM4EHPGDSMN1; SMN2 | |
| SCHEMBL17506814 | 0.83 | CYP3A4 (0.52) | CYP3A4TSHRBRAFMAPTKDM4E | |
| SCHEMBL22102775 | 0.83 | MAPT (0.65) | CYP3A4TSHRMAPTKDM4EHPGD | |
| SCHEMBL20268581 | 0.82 | MAPT (0.59) | CYP3A4MAPTKDM4EHPGDSMN1; SMN2 | |
| SCHEMBL20285744 | 0.80 | CYP3A4 (0.42) | CYP3A4TSHRBRAFMAPTKDM4E | |
| SCHEMBL17506813 | 0.80 | CYP3A4 (0.55) | CYP3A4TSHRBRAFMAPTKDM4E | |
| SCHEMBL20268378 | 0.79 | MAPT (0.56) | CYP3A4MAPTKDM4EHPGDSMN1; SMN2 | |
| SCHEMBL17527023 | 0.77 | RAPGEF4 (0.54) | CYP3A4TSHRBRAFMAPTALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3554466-B1 | DISSYMMETRIC AZOMETHINE DIRECT DYES AND PROCESS FOR THEIR PREPARATION, COSMETIC COMPOSITION COMPRISING AT LEAST ONE SUCH DYE AND USE THEREOF | OREAL (FR) | 2020-11-25 | — | — | EP | claimed |
| US-10927259-B2 | Dissymmetric azomethine direct dyes and process for their preparation, cosmetic composition comprising at least one such dye and use thereof | L'OREAL (FR) | 2021-02-23 | — | — | US | disclosed |
| EP-3554466-B1 | DISSYMMETRIC AZOMETHINE DIRECT DYES AND PROCESS FOR THEIR PREPARATION, COSMETIC COMPOSITION COMPRISING AT LEAST ONE SUCH DYE AND USE THEREOF | OREAL (FR) | 2020-11-25 | — | — | EP | disclosed |
| EP-3554466-B1 | DISSYMMETRIC AZOMETHINE DIRECT DYES AND PROCESS FOR THEIR PREPARATION, COSMETIC COMPOSITION COMPRISING AT LEAST ONE SUCH DYE AND USE THEREOF | OREAL (FR) | 2020-11-25 | — | — | EP | disclosed |
| US-20200190329-A1 | DISSYMMETRIC AZOMETHINE DIRECT DYES AND PROCESS FOR THEIR PREPARATION, COSMETIC COMPOSITION COMPRISING AT LEAST ONE SUCH DYE AND USE THEREOF | L'OREAL (FR) | 2020-06-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10927259-B2 | Dissymmetric azomethine direct dyes and process for their preparation, cosmetic composition comprising at least one such dye and use thereof | KRT18, DSG1, IK | CYP3A4 1251/4885TSHR 2280/4885BRAF 600/4885 |
| US-20200190329-A1 | DISSYMMETRIC AZOMETHINE DIRECT DYES AND PROCESS FOR THEIR PREPARATION, COSMETIC COMPOSITION COMPRISING AT LEAST ONE SUCH DYE AND USE THEREOF | KRT18, DSG1, IK | CYP3A4 1251/4885TSHR 2280/4885BRAF 600/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.