Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 13/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.65 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.65 |
| ▸ | HTT | P42858 | 3/20 | 0.65 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.65 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.65 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.65 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.65 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.62 |
| ▸ | HPGD | P15428 | 3/20 | 0.62 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.62 |
| ▸ | TP53 | P04637 | 1/20 | 0.62 |
| ▸ | APP | P05067 | 1/20 | 0.62 |
| ▸ | SNCA | P37840 | 1/20 | 0.62 |
| ▸ | BLM | P54132 | 1/20 | 0.62 |
| ▸ | GAA | P10253 | 10/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20268581 | 0.92 | MAPT (0.59) | MAPTALDH1A1L3MBTL1HTTCYP1A2 | |
| SCHEMBL5080900 | 0.92 | MAPT (0.64) | MAPTALDH1A1L3MBTL1HTTCYP1A2 | |
| Hydrochloric Acid SCHEMBL9797327 | 0.90 | MAPT (0.61) | MAPTALDH1A1L3MBTL1HTTCYP1A2 | |
| SCHEMBL22683200 | 0.85 | MAPT (0.61) | MAPTALDH1A1L3MBTL1HTTCYP1A2 | |
| SCHEMBL5084625 | 0.85 | MAPT (0.67) | MAPTALDH1A1L3MBTL1HTTCYP1A2 | |
| SCHEMBL7011541 | 0.83 | MAPT (0.77) | MAPTALDH1A1L3MBTL1HTTCYP1A2 | |
| SCHEMBL22102771 | 0.83 | CYP3A4 (0.53) | MAPTALDH1A1L3MBTL1HTTCYP1A2 | |
| SCHEMBL22701403 | 0.82 | MAPT (0.56) | MAPTALDH1A1L3MBTL1HTTCYP1A2 | |
| SCHEMBL20285584 | 0.82 | MAPT (0.51) | MAPTALDH1A1L3MBTL1HTTCYP1A2 | |
| SCHEMBL3425246 | 0.82 | GAA (0.63) | MAPTALDH1A1L3MBTL1HTTCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10927259-B2 | Dissymmetric azomethine direct dyes and process for their preparation, cosmetic composition comprising at least one such dye and use thereof | L'OREAL (FR) | 2021-02-23 | — | — | US | disclosed |
| EP-3554466-B1 | DISSYMMETRIC AZOMETHINE DIRECT DYES AND PROCESS FOR THEIR PREPARATION, COSMETIC COMPOSITION COMPRISING AT LEAST ONE SUCH DYE AND USE THEREOF | OREAL (FR) | 2020-11-25 | — | — | EP | disclosed |
| US-20200190329-A1 | DISSYMMETRIC AZOMETHINE DIRECT DYES AND PROCESS FOR THEIR PREPARATION, COSMETIC COMPOSITION COMPRISING AT LEAST ONE SUCH DYE AND USE THEREOF | L'OREAL (FR) | 2020-06-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10927259-B2 | Dissymmetric azomethine direct dyes and process for their preparation, cosmetic composition comprising at least one such dye and use thereof | KRT18, DSG1, IK | MAPT 862/4885ALDH1A1 754/4885L3MBTL1 3750/4885 |
| US-20200190329-A1 | DISSYMMETRIC AZOMETHINE DIRECT DYES AND PROCESS FOR THEIR PREPARATION, COSMETIC COMPOSITION COMPRISING AT LEAST ONE SUCH DYE AND USE THEREOF | KRT18, DSG1, IK | MAPT 862/4885ALDH1A1 754/4885L3MBTL1 3750/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.