Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNQ3 | O43525 | 5/20 | 0.36 |
| ▸ | KCNQ2 | O43526 | 5/20 | 0.36 |
| ▸ | JAK2 | O60674 | 3/20 | 0.35 |
| ▸ | JAK3 | P52333 | 3/20 | 0.35 |
| ▸ | SYK | P43405 | 5/20 | 0.35 |
| ▸ | ZAP70 | P43403 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | IRAK4 | Q9NWZ3 | 4/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.33 |
| ▸ | PIK3R2 | O00459 | 1/20 | 0.33 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29359724 | 0.74 | HTR6 (0.49) | KCNQ3KCNQ2IRAK4HPGDSMN1; SMN2 | |
| SCHEMBL22102600 | 0.72 | HTR6 (0.41) | IRAK4HPGDPIK3CDPIK3R2PIK3CG | |
| SCHEMBL25261273 | 0.71 | KCNQ3 (0.43) | KCNQ3KCNQ2ALDH1A1TSHRHPGD | |
| SCHEMBL17657041 | 0.70 | PIK3CG (0.45) | JAK2JAK3IRAK4PIK3CDPIK3R2 | |
| SCHEMBL31061409 | 0.70 | IRAK4 (0.40) | JAK2JAK3IRAK4HPGDPIK3CD | |
| SCHEMBL22102607 | 0.69 | NTRK1 (0.51) | ALDH1A1IRAK4HPGDSMN1; SMN2PIK3CD | |
| SCHEMBL462895 | 0.69 | HPGD (0.41) | ALDH1A1IRAK4HPGDSMN1; SMN2PIK3CD | |
| SCHEMBL22102625 | 0.68 | HTR6 (0.43) | KCNQ3KCNQ2IRAK4HPGDPIK3CD | |
| SCHEMBL23216990 | 0.68 | HPGD (0.40) | KCNQ3KCNQ2JAK2JAK3ALDH1A1 | |
| SCHEMBL23217145 | 0.67 | JAK2 (0.38) | KCNQ3KCNQ2JAK2JAK3SYK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020119592-A1 | NOVEL THREE-RING FUSED STRUCTURE COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF | 信达生物制药(苏州)有限公司 | 2020-06-18 | — | — | WO | disclosed |