SCHEMBL22103756

SCHEMBL22103756

Cc1ccc2oc(-c3ccc(N(c4ccc(-c5nc6ccccc6o5)cc4)c4ccc(-c5nc6cc(N)ccc6o5)cc4)cc3)nc2c1

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 18/20 0.68
NPC1 O15118 16/20 0.68
KDM4E B2RXH2 11/20 0.68
SMN1; SMN2 Q16637 11/20 0.68
MAPT P10636 10/20 0.68
ALDH1A1 P00352 9/20 0.68
TP53 P04637 7/20 0.68
HSD17B10 Q99714 6/20 0.68
NFKB1 P19838 3/20 0.68
NFKB2 Q00653 3/20 0.68
RELA Q04206 3/20 0.68
L3MBTL1 Q9Y468 2/20 0.68
MEN1 O00255 4/20 0.64
KMT2A Q03164 4/20 0.64
CASP3 P42574 3/20 0.64
RXFP1 Q9HBX9 2/20 0.64
HPGD P15428 7/20 0.60
SENP8 Q96LD8 2/20 0.60
SENP7 Q9BQF6 2/20 0.60
SENP6 Q9GZR1 2/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24205727 0.93 RAB9A (0.69) RAB9ANPC1KDM4ESMN1; SMN2MAPT
SCHEMBL24205685 0.93 RAB9A (0.69) RAB9ANPC1KDM4ESMN1; SMN2MAPT
SCHEMBL24205753 0.85 NPC1 (0.62) RAB9ANPC1KDM4ESMN1; SMN2MAPT
SCHEMBL24205684 0.85 NPC1 (0.62) RAB9ANPC1KDM4ESMN1; SMN2MAPT
SCHEMBL10047620 0.84 NPC1 (0.56) RAB9ANPC1KDM4ESMN1; SMN2MAPT
SCHEMBL12249738 0.82 NPC1 (0.56) RAB9ANPC1KDM4ESMN1; SMN2MAPT
SCHEMBL10315400 0.82 KDM4E (0.65) RAB9ANPC1KDM4ESMN1; SMN2MAPT
SCHEMBL474369 0.82 RAB9A (0.82) RAB9ANPC1KDM4ESMN1; SMN2MAPT
SCHEMBL2245029 0.82 RAB9A (1.00) RAB9ANPC1KDM4ESMN1; SMN2MAPT
SCHEMBL31154077 0.82 RAB9A (0.82) RAB9ANPC1KDM4ESMN1; SMN2MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020122359-A1 TRIBENZAZOLE AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING SAME 주식회사 랩토 2020-06-18 WO disclosed