Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 15/20 | 0.82 |
| ▸ | NPC1 | O15118 | 14/20 | 0.82 |
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.82 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.82 |
| ▸ | SMN1; SMN2 | Q16637 | 9/20 | 0.82 |
| ▸ | MAPT | P10636 | 8/20 | 0.82 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.82 |
| ▸ | TP53 | P04637 | 5/20 | 0.82 |
| ▸ | NFKB1 | P19838 | 5/20 | 0.82 |
| ▸ | NFKB2 | Q00653 | 5/20 | 0.82 |
| ▸ | RELA | Q04206 | 5/20 | 0.82 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.82 |
| ▸ | HPGD | P15428 | 8/20 | 0.81 |
| ▸ | GFER | P55789 | 2/20 | 0.76 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.76 |
| ▸ | CASP3 | P42574 | 3/20 | 0.71 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.71 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.71 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.71 |
| ▸ | POLB | P06746 | 1/20 | 0.71 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31154077 | 1.00 | RAB9A (0.82) | RAB9ANPC1KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL14947173 | 0.92 | ALDH1A1 (0.96) | RAB9ANPC1KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL2245029 | 0.90 | RAB9A (1.00) | RAB9ANPC1KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL3288386 | 0.90 | ALDH1A1 (1.00) | RAB9ANPC1KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL15047797 | 0.90 | ALDH1A1 (0.93) | RAB9ANPC1KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL2247430 | 0.87 | NPC1 (0.77) | RAB9ANPC1KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL5654856 | 0.86 | RAB9A (0.86) | RAB9ANPC1KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL29603993 | 0.86 | RAB9A (0.86) | RAB9ANPC1KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL29404722 | 0.86 | RAB9A (1.00) | RAB9ANPC1KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL1852701 | 0.86 | RAB9A (1.00) | RAB9ANPC1KDM4EALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220017503-A1 | TRIBENZAZOLE AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING SAME | LAPTO CO., LTD. (KR) | 2022-01-20 | — | — | US | disclosed |
| CN-111620833-A | Preparation method of 2-phenylbenzoxazole compound | 青岛伯川特聚科技有限公司 | 2020-09-04 | — | — | CN | disclosed |
| EP-2112206-B1 | Polymer Composition | ROHM & HAAS (US) | 2016-06-29 | — | — | EP | disclosed |
| EP-2166043-B1 | Thickener composition and method for thickening aqueous systems | ROHM & HAAS (US) | 2016-04-27 | — | — | EP | disclosed |
| US-8330039-B2 | Solar cell modules with poly(vinyl butyral) encapsulant comprising unsaturated heterocyclic compound | E I DU PONT DE NEMOURS AND COMPANY (US) | 2012-12-11 | — | — | US | disclosed |
| EP-2166044-B1 | Thickened compositions and method for thickening aqueous polymer compositions | ROHM & HAAS (US) | 2012-02-01 | — | — | EP | disclosed |
| US-20110281980-A1 | Thickener composition and method for thickening aqueous systems | BOBSEIN BARRETT RICHARD (US) | 2011-11-17 | — | — | US | disclosed |
| EP-2380208-A1 | SOLAR CELL MODULES WITH POLY(VINYL BUTYRAL) ENCAPSULANT COMPRISING UNSATURATED HETEROCYCLIC COMPOUND | E. I. du Pont de Nemours and Company (US) | 2011-10-26 | — | — | EP | disclosed |
| US-8034869-B2 | Thickened compositions and method for thickening aqueous polymer compositions | ROHM AND HAAS COMPANY (US) | 2011-10-11 | — | — | US | disclosed |
| US-7985795-B2 | Thickener composition and method for thickening aqueous systems | ROHM AND HAAS COMPANY (US) | 2011-07-26 | — | — | US | disclosed |
| CN-1930121-A | Substituted heteroaryl- and phenylsulfamoyl compounds | PFIZER PROD INC (US) | 2007-03-14 | — | — | CN | disclosed |
| US-20060258723-A1 | Substituted Heteroaryl- and Phenylsulfamoyl Compounds | PFIZER INC | 2006-11-16 | — | — | US | disclosed |
| US-20050228015-A1 | Substituted heteroaryl- and phenylsulfamoyl compounds | PFIZER INC | 2005-10-13 | — | — | US | disclosed |
| EP-0688830-B1 | Azo compounds and polarizing films using the compounds | MITSUI CHEMICALS INC (JP) | 1998-11-18 | — | — | EP | disclosed |
| US-5698682-A | HIGH HEAT RESISTANCE; EXCELLENT OPTICAL PROPERTIES; DICHROIC DYES | MITSUI TOATSU CHEMICALS, INC. (JP) | 1997-12-16 | — | — | US | disclosed |
| US-5639809-A | AZO COMPOUND DISTRIBUTED IN POLYMER FILM; HEAT RESISTANCE | MITSUI TOATSU CHEMICALS, INC. (JP) | 1997-06-17 | — | — | US | disclosed |
| EP-0527704-B1 | Dyestuffs, process for their preparation and the use thereof | CIBA GEIGY AG (CH) | 1996-08-28 | — | — | EP | disclosed |
| EP-0688830-A1 | Azo compounds and polarizing films using the compounds | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1995-12-27 | — | — | EP | disclosed |
| US-5302704-A | For dyeing polyamide fibers; colorfastness | CIBA-GEIGY CORPORATION (US) | 1994-04-12 | — | — | US | disclosed |
| EP-0527704-A2 | Dyestuffs, process for their preparation and the use thereof | CIBA-GEIGY AG (CH) | 1993-02-17 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050228015-A1 | Substituted heteroaryl- and phenylsulfamoyl compounds | PPARA, PPARG, PPARD | RAB9A 2271/4885NPC1 59/4885KDM4E 3834/4885 |
| US-20060258723-A1 | Substituted Heteroaryl- and Phenylsulfamoyl Compounds | PPARG, PPARA, PPARD | RAB9A 2063/4885NPC1 74/4885KDM4E 3815/4885 |
| US-20220017503-A1 | TRIBENZAZOLE AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING SAME | CYP2E1, CYP1B1, ODC1 | RAB9A 2949/4885NPC1 4030/4885KDM4E 1101/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.