SCHEMBL22105163

SCHEMBL22105163

CCCCCc1cc(O)c2c(c1)OC(C)C=C2

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ CNR1 P21554 9/20 0.49
▸ CNR2 P34972 9/20 0.49
▸ TRPV1 Q8NER1 4/20 0.49
▸ LDHA P00338 2/20 0.49
▸ TRPM8 Q7Z2W7 2/20 0.49
▸ TRPA1 O75762 1/20 0.49
▸ SLC6A2 P23975 1/20 0.49
▸ SLC6A4 P31645 1/20 0.49
▸ SLC6A3 Q01959 1/20 0.49
▸ TRPV3 Q8NET8 1/20 0.49
▸ TRPV4 Q9HBA0 1/20 0.49
▸ TRPV2 Q9Y5S1 1/20 0.49
▸ PTGS2 P35354 3/20 0.44
▸ CYP3A4 P08684 1/20 0.44
▸ NPC1 O15118 1/20 0.42
▸ HPGD P15428 1/20 0.42
▸ MAPK1 P28482 1/20 0.42
▸ HTT P42858 1/20 0.42
▸ RAB9A P51151 1/20 0.42
▸ NPSR1 Q6W5P4 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31759056 1.00 CNR1 (0.49) CNR1CNR2TRPV1LDHATRPM8
SCHEMBL25367932 0.80 DAO (0.40) CNR1CNR2PTGS2HPGD
SCHEMBL31056925 0.75 CNR1 (0.51) CNR1CNR2SLC6A3NR1I2GLRA1
SCHEMBL21821203 0.74 CNR2 (0.49) CNR1CNR2TRPV1LDHATRPM8
SCHEMBL31056759 0.74 CNR2 (0.49) CNR1CNR2TRPV1LDHATRPM8
SCHEMBL22069530 0.73 CNR2 (0.67) CNR1CNR2TRPV1LDHATRPM8
SCHEMBL22942198 0.69 TRPV1 (0.50) CNR1CNR2TRPV1LDHATRPM8
SCHEMBL31545281 0.69 TRPV1 (0.50) CNR1CNR2TRPV1LDHATRPM8
SCHEMBL6356508 0.69 PTGS2 (0.65) TRPV1SLC6A2SLC6A4SLC6A3PTGS2
SCHEMBL5788838 0.67 PTGS2 (0.67) SLC6A2SLC6A4SLC6A3PTGS2CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260007688-A1 SYNTHETIC ANALOGS OF CANNABINOL (CBN) FOR THE TREATMENT OF AGERELATED NEUROLOGICAL DISORDERS SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) 2026-01-08 — — US claimed
WO-2024148193-A1 SYNTHETIC ANALOGS OF CANNABINOL (CBN) FOR THE TREATMENT OF AGE-RELATED NEUROLOGICAL DISORDERS SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) 2024-07-11 — — WO claimed
US-20260007688-A1 SYNTHETIC ANALOGS OF CANNABINOL (CBN) FOR THE TREATMENT OF AGERELATED NEUROLOGICAL DISORDERS SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) 2026-01-08 — — US disclosed
WO-2024148193-A1 SYNTHETIC ANALOGS OF CANNABINOL (CBN) FOR THE TREATMENT OF AGE-RELATED NEUROLOGICAL DISORDERS SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) 2024-07-11 — — WO disclosed
EP-3666765-A1 CHROMENIC PHYTOCANNABINOIDS, THEIR SYNTHESIS AND USE IN TREATMENT OR PREVENTION OF DISEASE Emerald Health Biotechnology España,S.L.U. (ES) 2020-06-17 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260007688-A1 SYNTHETIC ANALOGS OF CANNABINOL (CBN) FOR THE TREATMENT OF AGERELATED NEUROLOGICAL DISORDERS AIFM2, FECH, NLN CNR1 5/4885CNR2 4/4885TRPV1 804/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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