Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.39 |
| ▸ | IDH1 | O75874 | 2/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 5/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22106241 | 0.89 | KDM4E (0.44) | KDM4EGLAGAANPSR1MEN1 | |
| SCHEMBL22106146 | 0.88 | KDM4E (0.46) | KDM4EGLAGAANPSR1MEN1 | |
| SCHEMBL23409414 | 0.81 | GAA (0.44) | KDM4EGAANPSR1MEN1KMT2A | |
| SCHEMBL22106274 | 0.81 | KDM4E (0.44) | KDM4EGLAGAANPSR1MEN1 | |
| SCHEMBL22106070 | 0.80 | GAA (0.43) | KDM4EGAANPSR1MEN1KMT2A | |
| SCHEMBL23003777 | 0.76 | GAA (0.48) | KDM4EGLAGAANPSR1MEN1 | |
| SCHEMBL16571344 | 0.76 | GAA (0.50) | KDM4EGLAGAANPSR1MEN1 | |
| SCHEMBL22095708 | 0.76 | THRB (0.63) | — | |
| SCHEMBL16571563 | 0.75 | KDM4E (0.51) | KDM4EGLAGAANPSR1KMT2A | |
| SCHEMBL24133259 | 0.74 | KDM4E (0.45) | KDM4EGLAGAANPSR1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11827596-B2 | Thyromimetics | AUTOBAHN THERAPEUTICS, INC. (US) | 2023-11-28 | — | — | US | disclosed |
| US-11827596-B2 | Thyromimetics | AUTOBAHN THERAPEUTICS, INC. (US) | 2023-11-28 | — | — | US | disclosed |
| US-11827596-B2 | Thyromimetics | AUTOBAHN THERAPEUTICS, INC. (US) | 2023-11-28 | — | — | US | disclosed |
| CN-113423684-A | Novel thyromimetic agents | 速通医疗公司 | 2021-09-21 | — | — | CN | disclosed |
| US-20200361849-A1 | NOVEL THYROMIMETICS | AUTOBAHN THERAPEUTICS, INC. | 2020-11-19 | — | — | US | disclosed |
| US-20200361849-A1 | NOVEL THYROMIMETICS | AUTOBAHN THERAPEUTICS, INC. | 2020-11-19 | — | — | US | disclosed |
| WO-2020123861-A1 | NOVEL THYROMIMETICS | AUTOBAHN THERAPEUTICS, INC. (US) | 2020-06-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200361849-A1 | NOVEL THYROMIMETICS | TPO, THOP1, TSHR | KDM4E 3853/4885GLA 540/4885GAA 1388/4885 |
| US-11827596-B2 | Thyromimetics | TPO, TSHR, TTR | KDM4E 3916/4885GLA 539/4885GAA 1574/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.