Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Phenanthroline. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.70 |
| ▸ | LMNA | P02545 | 4/20 | 0.70 |
| ▸ | MAPT | P10636 | 4/20 | 0.70 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.70 |
| ▸ | HTT | P42858 | 3/20 | 0.70 |
| ▸ | CCR1 | P32246 | 3/20 | 0.70 |
| ▸ | CCR5 | P51681 | 3/20 | 0.70 |
| ▸ | CCR8 | P51685 | 3/20 | 0.70 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.70 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.70 |
| ▸ | MMP2 | P08253 | 2/20 | 0.70 |
| ▸ | TSHR | P16473 | 2/20 | 0.70 |
| ▸ | GMNN | O75496 | 1/20 | 0.70 |
| ▸ | TP53 | P04637 | 1/20 | 0.70 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.70 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.70 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.70 |
| ▸ | MMP9 | P14780 | 1/20 | 0.70 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.70 |
| ▸ | MMP8 | P22894 | 1/20 | 0.70 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phenanthroline SCHEMBL623252 | 1.00 | KDM4E (0.70) | KDM4ELMNAMAPTTDP1HTT | |
| Phenanthroline SCHEMBL30613730 | 1.00 | KDM4E (0.70) | KDM4ELMNAMAPTTDP1HTT | |
| Phenanthroline SCHEMBL8722750 | 0.96 | KDM4E (0.70) | KDM4ELMNAMAPTTDP1HTT | |
| Phenanthroline SCHEMBL6045190 | 0.96 | KDM4E (0.70) | KDM4ELMNAMAPTTDP1HTT | |
| Phenanthroline SCHEMBL29278209 | 0.96 | KDM4E (0.70) | KDM4ELMNAMAPTTDP1HTT | |
| Phenanthroline SCHEMBL8686399 | 0.96 | KDM4E (0.70) | KDM4ELMNAMAPTTDP1HTT | |
| Phenanthroline SCHEMBL5888427 | 0.94 | KDM4E (0.67) | KDM4ELMNAMAPTTDP1HTT | |
| Phenanthroline SCHEMBL30868492 | 0.86 | CCR1 (0.94) | KDM4ELMNAMAPTTDP1HTT | |
| Phenanthroline SCHEMBL29376843 | 0.86 | CCR1 (0.94) | KDM4ELMNAMAPTTDP1HTT | |
| Phenanthroline SCHEMBL11867003 | 0.84 | KDM4E (0.73) | KDM4ELMNAMAPTTDP1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 110 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250251347-A1 | PORTABLE LIQUID ANALYZER | VERITEQUE USA INC (US) | 2025-08-07 | — | — | US | claimed |
| US-11940387-B2 | Portable liquid analyzer | VERITEQUE USA, INC. (US) | 2024-03-26 | — | — | US | claimed |
| WO-2023135469-A1 | WOUND CARE COVERING | Boock Engineering LLC (US) | 2023-07-20 | — | — | WO | claimed |
| US-20230226251-A1 | WOUND CARE COVERING | Boock Engineering LLC (US) | 2023-07-20 | — | — | US | claimed |
| US-10942126-B2 | Portable liquid analyzer | S2 DETECTION NEVADA, INC. (US) | 2021-03-09 | — | — | US | claimed |
| US-20200371038-A1 | PORTABLE LIQUID ANALYZER | S2 DETECTION (NEVADA) INC. | 2020-11-26 | — | — | US | claimed |
| US-20190353597-A1 | PORTABLE LIQUID ANALYZER | VERITEQUE USA, INC. | 2019-11-21 | — | — | US | claimed |
| US-9989473-B2 | Portable liquid analyzer | VERITEQUE USA, INC. | 2018-06-05 | — | — | US | claimed |
| US-20170315436-A1 | PHOTOCATALYTIC COLOR SWITCHING OF REDOX IMAGING NANOMATERIALS OF REWRITABLE MEDIA | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2017-11-02 | — | — | US | claimed |
| US-20170082550-A1 | PORTABLE LIQUID ANALYZER | VERITEQUE USA, INC. | 2017-03-23 | — | — | US | claimed |
| EP-4733331-A2 | METHODS OF CHROMIUM CATALYST ACTIVATION TO REDUCE GELS AND IMPROVE MELT INDEX POTENTIAL | Chevron Phillips Chemical Company LP (US) | 2026-04-29 | — | — | EP | disclosed |
| US-12606725-B2 | Adhesive tape roll with color-changing dye | KORAVOS DAVID FRANKLIN (US) | 2026-04-21 | — | — | US | disclosed |
| EP-4705360-A1 | METHODS OF CHROMIUM CATALYST ACTIVATION TO REDUCE GELS AND IMPROVE MELT INDEX POTENTIAL | Chevron Phillips Chemical Company LP (US) | 2026-03-11 | — | — | EP | disclosed |
| US-20260062709-A1 | METHODS FOR IMPROVING PRODUCTION OF BIOLOGICAL PRODUCTS BY REDUCING THE LEVEL OF ENDOGENOUS PROTEIN | LONZA AG (CH) | 2026-03-05 | — | — | US | disclosed |
| US-12565545-B2 | Particle size control of silyl chromate catalysts and uses thereof in fluidized bed reactors | CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) | 2026-03-03 | — | — | US | disclosed |
| EP-0661299-B1 | Chromium catalyst compositions and ethylene polymerization processes therewith | PHILLIPS PETROLEUM CO (US) | 2001-07-25 | — | — | EP | disclosed |
| US-6054039-A | BY MEANS OF AN AMPEROMETRIC BIOSENSOR | SHIEH PAUL (US) | 2000-04-25 | — | — | US | disclosed |
| US-5599887-A | ON SILICA CATALYST SUPPORT | PHILLIPS PETROLEUM COMPANY (US) | 1997-02-04 | — | — | US | disclosed |
| US-5576263-A | DECREASED DIE SWELL | PHILLIPS PETROLEUM COMPANY (US) | 1996-11-19 | — | — | US | disclosed |
| EP-0661299-A2 | Chromium catalyst compositions and ethylene polymerization processes therewith | PHILLIPS PETROLEUM COMPANY (US) | 1995-07-05 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12565545-B2 | Particle size control of silyl chromate catalysts and uses thereof in fluidized bed reactors | SAMM50, GSTM2, MCM4 | KDM4E 2078/4885LMNA 2182/4885MAPT 3721/4885 |
| US-12606725-B2 | Adhesive tape roll with color-changing dye | TELO2, EPCAM, TDO2 | KDM4E 1248/4885LMNA 1078/4885MAPT 190/4885 |
| US-20260062709-A1 | METHODS FOR IMPROVING PRODUCTION OF BIOLOGICAL PRODUCTS BY REDUCING THE LEVEL OF ENDOGENOUS PROTEIN | MRPL21, SET, RPS27A | KDM4E 3663/4885LMNA 3180/4885MAPT 2146/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.