Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFE2L2 | Q16236 | 5/20 | 0.38 |
| ▸ | ACHE | P22303 | 4/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 3/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.32 |
| ▸ | TP53 | P04637 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.31 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.31 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6793057 | 0.78 | ALDH1A1 (0.42) | NFE2L2ACHECYP2A6CYP1A2TDP1 | |
| SCHEMBL20811520 | 0.77 | NFE2L2 (0.38) | NFE2L2ACHECYP2A6TDP1SMN1; SMN2 | |
| SCHEMBL19929310 | 0.76 | NFE2L2 (0.46) | NFE2L2ACHECYP2A6CYP1A2THRB | |
| SCHEMBL17529908 | 0.75 | TDP1 (0.44) | ACHECYP2A6CYP1A2TDP1TP53 | |
| SCHEMBL25449169 | 0.71 | TDP1 (0.54) | ACHECYP2A6CYP1A2TDP1TP53 | |
| SCHEMBL29441288 | 0.71 | — | — | |
| SCHEMBL130515 | 0.71 | — | — | |
| SCHEMBL11308895 | 0.70 | TDP1 (0.44) | ACHECYP2A6CYP1A2TDP1TP53 | |
| Ammonia Solution, Strong SCHEMBL20593640 | 0.69 | NFE2L2 (0.60) | NFE2L2ACHECYP2A6CYP1A2TDP1 | |
| SCHEMBL13520606 | 0.69 | GRM2 (0.44) | NFE2L2ACHECYP2A6CYP1A2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3893872-B1 | ORGANOPHOSPHORUS-SUBSTITUTED COMPOUNDS AS C-MET INHIBITORS AND THERAPEUTIC USES THEREOF | BETA PHARMA INC (US) | 2024-07-17 | — | — | EP | disclosed |
| WO-2020124060-A1 | ORGANOPHOSPHORUS-SUBSTITUTED COMPOUNDS AS C-MET INHIBITORS AND THERAPEUTIC USES THEREOF | BETA PHARMA, INC. (US) | 2020-06-18 | — | — | WO | disclosed |