SCHEMBL6793057

SCHEMBL6793057

CP(C)c1ccc(F)cc1F

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.42
CES2 O00748 2/20 0.38
CES1 P23141 2/20 0.38
CA3 P07451 1/20 0.37
CA6 P23280 1/20 0.37
CA5A P35218 1/20 0.37
CA9 Q16790 1/20 0.37
CA14 Q9ULX7 1/20 0.37
CA5B Q9Y2D0 1/20 0.37
TDP1 Q9NUW8 2/20 0.35
ATM Q13315 1/20 0.35
NFE2L2 Q16236 3/20 0.34
IDO1 P14902 2/20 0.34
AGXT P21549 2/20 0.34
HTT P42858 1/20 0.33
ACHE P22303 2/20 0.32
CYP1A2 P05177 1/20 0.32
CYP2A6 P11509 1/20 0.32
MEN1 O00255 1/20 0.32
POLB P06746 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29716617 0.79 ALDH1A1 (0.46) ALDH1A1CES2CES1CA3CA6
SCHEMBL19921795 0.79 ALDH1A1 (0.46) ALDH1A1CES2CES1CA3CA6
SCHEMBL22109503 0.78 NFE2L2 (0.38) ALDH1A1TDP1NFE2L2ACHECYP1A2
SCHEMBL29349450 0.75 ALDH1A1 (0.42) ALDH1A1CES2CES1CA3CA6
SCHEMBL8019931 0.75 ALDH1A1 (0.42) ALDH1A1CES2CES1CA3CA6
SCHEMBL29350421 0.75 ALDH1A1 (0.42) ALDH1A1CES2CES1CA3CA6
SCHEMBL19968270 0.75 ALDH1A1 (0.42) ALDH1A1CES2CES1CA3CA6
SCHEMBL2883739 0.75 ALDH1A1 (0.42) ALDH1A1CES2CES1CA3CA6
SCHEMBL29350948 0.75 ALDH1A1 (0.42) ALDH1A1CES2CES1CA3CA6
SCHEMBL12620092 0.75 CES2 (0.43) ALDH1A1CES2CES1CA3CA6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6822057-B2 OLEFIN POLYMERIZATION CATALYST SYSTEM IS A REACTION PRODUCT OF A METALLOCENES AND A COCATALYST CONTAINING FLUOROARYL SUBSTITUTED SECONDARY AMINE OR PHSOPHINE COMPOUND AND AN ANION CONTAINING GROUP 13 ELEMENT WHICH IS NONCOORDINATIG EXXON MOBIL CHEMICAL PATENTS INC. 2004-11-23 US disclosed
US-6489480-B2 COORDINATION POLYMERIZATION CATALYST FOR ALPHA-OLEFINS EXXONMOBIL CHEMICAL PATENTS INC. 2002-12-03 US disclosed
US-20020115806-A1 Olefin polymerization catalysts derived from Group-15 cationic compounds and processes using them EXXONMOBIL CHEMICAL PATENTS INC. 2002-08-22 US disclosed
US-20020111265-A1 GROUP-15 CATIONIC COMPOUNDS FOR OLEFIN POLYMERIZATION CATALYSTS EXXONMOBIL CHEMICAL PATENTS INC. 2002-08-15 US disclosed