Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 1/20 | 0.63 |
| ▸ | CA1 | P00915 | 1/20 | 0.63 |
| ▸ | CA2 | P00918 | 1/20 | 0.63 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.63 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.63 |
| ▸ | ITGAL | P20701 | 1/20 | 0.63 |
| ▸ | CA4 | P22748 | 1/20 | 0.63 |
| ▸ | CA6 | P23280 | 1/20 | 0.63 |
| ▸ | AHR | P35869 | 1/20 | 0.63 |
| ▸ | ADK | P55263 | 1/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Indole SCHEMBL28123401 | 1.00 | TRPA1 (0.63) | TRPA1CA1CA2ITGB2ICAM1 | |
| Indole SCHEMBL21495202 | 0.88 | TRPA1 (0.49) | TRPA1CA1CA2ITGB2ICAM1 | |
| Naphthalene SCHEMBL29363450 | 0.86 | KDM4E (0.46) | TRPA1CA1CA2ITGB2ICAM1 | |
| Naphthalene SCHEMBL15819597 | 0.86 | KDM4E (0.46) | TRPA1CA1CA2ITGB2ICAM1 | |
| Naphthalene SCHEMBL9738608 | 0.86 | KDM4E (0.46) | TRPA1CA1CA2ITGB2ICAM1 | |
| Benzimidazole SCHEMBL29408372 | 0.84 | — | — | |
| Benzimidazole SCHEMBL29358377 | 0.84 | — | — | |
| Benzimidazole SCHEMBL461969 | 0.84 | SMN1; SMN2 (0.50) | KDM4EALDH1A1SMN1; SMN2HPGDRAB9A | |
| Benzimidazole SCHEMBL10931770 | 0.84 | SMN1; SMN2 (0.50) | KDM4EALDH1A1SMN1; SMN2HPGDRAB9A | |
| Benzimidazole SCHEMBL6009 | 0.84 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 51 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116003390-B | Indole-benzimidazole derivative fluorescent probe and preparation method and application thereof | 焦作师范高等专科学校 | 2024-03-08 | — | — | CN | claimed |
| CN-116003390-A | Indole-benzimidazole derivative fluorescent probe and preparation method and application thereof | 焦作师范高等专科学校 | 2023-04-25 | — | — | CN | claimed |
| CN-116003390-B | Indole-benzimidazole derivative fluorescent probe and preparation method and application thereof | 焦作师范高等专科学校 | 2024-03-08 | — | — | CN | disclosed |
| CN-116003390-B | Indole-benzimidazole derivative fluorescent probe and preparation method and application thereof | 焦作师范高等专科学校 | 2024-03-08 | — | — | CN | disclosed |
| CN-117343108-A | Organic electroluminescent material and device | 环球展览公司 | 2024-01-05 | — | — | CN | disclosed |
| CN-116744710-A | Organic electroluminescent material and device | 环球展览公司 | 2023-09-12 | — | — | CN | disclosed |
| CN-116003390-A | Indole-benzimidazole derivative fluorescent probe and preparation method and application thereof | 焦作师范高等专科学校 | 2023-04-25 | — | — | CN | disclosed |
| CN-116003390-A | Indole-benzimidazole derivative fluorescent probe and preparation method and application thereof | 焦作师范高等专科学校 | 2023-04-25 | — | — | CN | disclosed |
| EP-4153700-A1 | LIQUID-CRYSTALLINE MEDIUM | Merck Patent GmbH (DE) | 2023-03-29 | — | — | EP | disclosed |
| CN-115215839-A | Indolyl benzimidazole near-infrared fluorescent dye and preparation method and application thereof | 南京林业大学 | 2022-10-21 | — | — | CN | disclosed |
| WO-2021233797-A1 | LIQUID-CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2021-11-25 | — | — | WO | disclosed |
| US-20050043509-A1 | Peptoid compounds | UNIVERSITY OF WOLLONGONG | 2005-02-24 | — | — | US | disclosed |
| EP-1412336-A1 | PEPTOID COMPOUNDS | UNIVERSITY OF WOLLONGONG (AU) | 2004-04-28 | — | — | EP | disclosed |
| EP-1028120-B1 | Organosilicon compounds with N-substituted benzimidazole-benzazole or benzofuranyl-benzazole groups, sunscreen compositions containing these compounds and their use | OREAL (FR) | 2003-03-19 | — | — | EP | disclosed |
| WO-2003002545-A1 | PEPTOID COMPOUNDS | UNIVERSITY OF WOLLONGONG (AU) | 2003-01-09 | — | — | WO | disclosed |
| CN-1267238-A | Homogeneous oxidation catalyst using metal complexes | UNIV CARNEGIE MELLON (US) | 2000-09-20 | — | — | CN | disclosed |
| EP-1028120-A1 | Organosilicon compounds with N-substituted benzimidazole-benzazole or benzofuranyl-benzazole groups, sunscreen compositions containing these compounds and their use | L'OREAL (FR) | 2000-08-16 | — | — | EP | disclosed |
| US-6037473-A | AS SUNSCREENS IN COSMETIC AND PHARMACEUTICAL PREPARATIONS; FOR ENHANCING PHOTOSTABILITY OF INDUSTRIAL PRODUCTS SUCH AS PAINTS, VARNISHES, PLASTICS, TEXTILES, PACKAGING MATERIALS AND RUBBERS | HAARMANN & REIMER GMBH (DE) | 2000-03-14 | — | — | US | disclosed |
| US-5961960-A | Use of substituted benzazoles as UV absorbers, new benzazoles and processes for their preparation | HAARMANN & REIMER GMBH (DE) | 1999-10-05 | — | — | US | disclosed |
| CN-1182742-A | Use of substituted benzazoles as UV absorbers, new benzazoles and processes for their preparation | HAARMANN & REIMER GMBH (DE) | 1998-05-27 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050043509-A1 | Peptoid compounds | VIP, FPR1, VIPR1 | TRPA1 155/4885CA1 4600/4885CA2 3977/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.