Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 12/20 | 0.56 |
| ▸ | OPRM1 | P35372 | 11/20 | 0.56 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | KDM1A | O60341 | 3/20 | 0.46 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | BCHE | P06276 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6583019 | 0.82 | MAOB (0.56) | KCNH2KDM1AMAOBBCHE | |
| SCHEMBL6588487 | 0.79 | SPHK1 (0.55) | KCNH2KDM1AMAOBBCHE | |
| SCHEMBL6583023 | 0.79 | SPHK1 (0.58) | KCNH2KDM1AMAOBBCHE | |
| SCHEMBL11075825 | 0.79 | OPRM1 (0.51) | OPRL1OPRM1KDM1AMAOBBCHE | |
| SCHEMBL22091656 | 0.78 | OPRL1 (0.53) | OPRL1OPRM1OPRK1 | |
| SCHEMBL24460873 | 0.78 | GRIN1 (0.53) | KCNH2KDM1AMAOBBCHE | |
| SCHEMBL22091686 | 0.78 | OPRL1 (0.58) | OPRL1OPRM1OPRK1MAOB | |
| SCHEMBL12354455 | 0.78 | SPHK1 (0.60) | KCNH2KDM1AMAOBBCHE | |
| SCHEMBL11075823 | 0.77 | OPRM1 (0.49) | OPRL1OPRM1KDM1AMAOBBCHE | |
| SCHEMBL11070020 | 0.77 | OPRM1 (0.49) | OPRL1OPRM1KDM1AMAOBBCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020120539-A1 | NEW PYRROLIDINE-2-CARBOXYLIC ACID DERIVATIVES FOR TREATING PAIN AND PAIN RELATED CONDITIONS | ESTEVE PHARMACEUTICALS, S.A. (ES) | 2020-06-18 | — | — | WO | disclosed |