Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 11/20 | 0.44 |
| ▸ | OPRL1 | P41146 | 10/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | OGFRL1 | Q5TC84 | 2/20 | 0.40 |
| ▸ | MAOB | P27338 | 2/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL517788 | 0.81 | OPRM1 (0.44) | OPRM1OPRL1OPRK1SLC6A2SLC6A4 | |
| SCHEMBL3407429 | 0.81 | OPRL1 (0.69) | OPRM1OPRL1OPRK1 | |
| SCHEMBL22112097 | 0.80 | OPRM1 (0.49) | OPRM1OPRL1OPRK1SLC6A2SLC6A4 | |
| SCHEMBL22112518 | 0.79 | SLC6A3 (0.58) | OPRM1OPRL1OPRK1SLC6A2SLC6A4 | |
| SCHEMBL14534174 | 0.74 | OPRM1 (0.46) | OPRM1OPRL1OPRK1SLC6A2SLC6A4 | |
| SCHEMBL4697957 | 0.73 | OPRM1 (0.42) | OPRM1OPRL1OPRK1OGFRL1 | |
| Hydrochloric Acid SCHEMBL2378965 | 0.72 | OPRM1 (0.41) | OPRM1OPRL1OPRK1OGFRL1 | |
| SCHEMBL13050538 | 0.70 | OPRM1 (0.44) | OPRM1OPRL1OPRK1SLC6A2SLC6A4 | |
| SCHEMBL12167362 | 0.70 | CYP2D6 (0.45) | OPRM1OPRL1OPRK1SLC6A2SLC6A4 | |
| Hydrochloric Acid SCHEMBL517996 | 0.70 | OPRM1 (0.46) | OPRM1OPRL1OPRK1SLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020120539-A1 | NEW PYRROLIDINE-2-CARBOXYLIC ACID DERIVATIVES FOR TREATING PAIN AND PAIN RELATED CONDITIONS | ESTEVE PHARMACEUTICALS, S.A. (ES) | 2020-06-18 | — | — | WO | disclosed |