Sugi Predict

Sugi Predict / Compounds / SCHEMBL2211239

SCHEMBL2211239

SCHEMBL2211239

Clc1ccc(CSc2nsc(SCc3ccc(Cl)cc3)n2)cc1

nearest known ligand 0.80

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ CYP2C19 P33261 2/20 0.80
▸ L3MBTL1 Q9Y468 2/20 0.80
▸ CYP1A2 P05177 1/20 0.80
▸ CYP2C9 P11712 1/20 0.80
▸ TDP1 Q9NUW8 3/20 0.71
▸ NPSR1 Q6W5P4 1/20 0.71
▸ MAPK1 P28482 2/20 0.57
▸ MEN1 O00255 3/20 0.53
▸ KMT2A Q03164 3/20 0.53
▸ ALDH1A1 P00352 3/20 0.49
▸ HSP90AA1 P07900 1/20 0.48
▸ RAB9A P51151 2/20 0.47
▸ SMN1; SMN2 Q16637 2/20 0.47
▸ ALOX15 P16050 1/20 0.47
▸ NPC1 O15118 1/20 0.47
▸ MGAM O43451 1/20 0.46
▸ GAA P10253 1/20 0.46
▸ SI P14410 1/20 0.46
▸ MGAM2 Q2M2H8 1/20 0.46
▸ HTT P42858 2/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12434046 0.93 L3MBTL1 (0.74) CYP2C19L3MBTL1CYP1A2CYP2C9TDP1
SCHEMBL4798493 0.85 L3MBTL1 (0.59) CYP2C19L3MBTL1CYP1A2CYP2C9TDP1
SCHEMBL11604444 0.82 L3MBTL1 (0.64) CYP2C19L3MBTL1CYP1A2CYP2C9TDP1
SCHEMBL11602726 0.73 CYP1A2 (0.56) CYP2C19L3MBTL1CYP1A2CYP2C9TDP1
SCHEMBL11607739 0.73 CYP1A2 (0.56) CYP2C19L3MBTL1CYP1A2CYP2C9TDP1
SCHEMBL5372995 0.73 ALOX15 (0.51) CYP2C19L3MBTL1CYP1A2CYP2C9TDP1
SCHEMBL17558052 0.73 MEN1 (0.66) CYP2C19L3MBTL1CYP1A2CYP2C9TDP1
SCHEMBL4797109 0.72 RAB9A (0.51) CYP2C19L3MBTL1CYP1A2CYP2C9TDP1
SCHEMBL4797641 0.71 RAB9A (0.66) CYP2C19L3MBTL1CYP1A2CYP2C9TDP1
SCHEMBL11601163 0.70 L3MBTL1 (0.53) CYP2C19L3MBTL1CYP1A2CYP2C9TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7785759-B2 Thiadiazole containing charge transport layer photoconductors XEROX CORPORATION (US) 2010-08-31 — — US claimed
US-20090246667-A1 THIADIAZOLE CONTAINING CHARGE TRANSPORT LAYER PHOTOCONDUCTORS XEROX CORPORATION (US) 2009-10-01 — — US claimed
US-20090246666-A1 THIADIAZOLE CONTAINING PHOTOCONDUCTORS XEROX CORPORATION (US) 2009-10-01 — — US claimed
US-7981579-B2 Thiadiazole containing photoconductors XEROX CORPORATION (US) 2011-07-19 — — US disclosed
US-7981579-B2 Thiadiazole containing photoconductors XEROX CORPORATION (US) 2011-07-19 — — US disclosed
US-7785759-B2 Thiadiazole containing charge transport layer photoconductors XEROX CORPORATION (US) 2010-08-31 — — US disclosed
US-7785759-B2 Thiadiazole containing charge transport layer photoconductors XEROX CORPORATION (US) 2010-08-31 — — US disclosed
US-7785759-B2 Thiadiazole containing charge transport layer photoconductors XEROX CORPORATION (US) 2010-08-31 — — US disclosed
US-20090246666-A1 THIADIAZOLE CONTAINING PHOTOCONDUCTORS XEROX CORPORATION (US) 2009-10-01 — — US disclosed
US-20090246667-A1 THIADIAZOLE CONTAINING CHARGE TRANSPORT LAYER PHOTOCONDUCTORS XEROX CORPORATION (US) 2009-10-01 — — US disclosed
US-20090246667-A1 THIADIAZOLE CONTAINING CHARGE TRANSPORT LAYER PHOTOCONDUCTORS XEROX CORPORATION (US) 2009-10-01 — — US disclosed
US-20090246666-A1 THIADIAZOLE CONTAINING PHOTOCONDUCTORS XEROX CORPORATION (US) 2009-10-01 — — US disclosed
US-20090246667-A1 THIADIAZOLE CONTAINING CHARGE TRANSPORT LAYER PHOTOCONDUCTORS XEROX CORPORATION (US) 2009-10-01 — — US disclosed
US-20090246666-A1 THIADIAZOLE CONTAINING PHOTOCONDUCTORS XEROX CORPORATION (US) 2009-10-01 — — US disclosed