Sugi Predict

Sugi Predict / Compounds / SCHEMBL22112409

SCHEMBL22112409

SCHEMBL22112409

c1ccc(-c2ccc(N(c3ccc(-c4ccccc4)cc3)c3cc(-c4nc(-c5ccccc5)nc(-c5ccccc5)n4)c4c(c3)oc3ccccc34)cc2)cc1

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 5/20 0.34
▸ KDM4E B2RXH2 3/20 0.34
▸ POLB P06746 2/20 0.34
▸ MAPT P10636 8/20 0.34
▸ TSHR P16473 5/20 0.34
▸ HPGD P15428 4/20 0.34
▸ LMNA P02545 3/20 0.34
▸ CYP1A2 P05177 2/20 0.34
▸ CYP3A4 P08684 2/20 0.34
▸ CYP2D6 P10635 2/20 0.34
▸ CYP2C9 P11712 2/20 0.34
▸ CYP2C19 P33261 2/20 0.34
▸ GLA P06280 1/20 0.34
▸ RECQL P46063 1/20 0.34
▸ SMN1; SMN2 Q16637 1/20 0.34
▸ HIF1A Q16665 1/20 0.34
▸ KDM1A O60341 1/20 0.34
▸ NR1H4 Q96RI1 1/20 0.34
▸ KMT2A Q03164 4/20 0.33
▸ HTT P42858 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24255426 0.99 ALDH1A1 (0.34) ALDH1A1KDM4EPOLBMAPTTSHR
SCHEMBL24255395 0.99 ALDH1A1 (0.34) ALDH1A1KDM4EPOLBMAPTTSHR
SCHEMBL24066080 0.95 TSHR (0.33) ALDH1A1KDM4EPOLBMAPTTSHR
SCHEMBL22112415 0.95 ALDH1A1 (0.36) ALDH1A1KDM4EPOLBMAPTTSHR
SCHEMBL26415419 0.94 MAPT (0.33) ALDH1A1KDM4EPOLBMAPTTSHR
SCHEMBL24066078 0.94 MMP12 (0.33) ALDH1A1KDM4EPOLBMAPTTSHR
SCHEMBL26415453 0.94 ALDH1A1 (0.36) ALDH1A1KDM4EPOLBMAPTTSHR
SCHEMBL24066124 0.93 KDM4E (0.36) ALDH1A1KDM4EPOLBMAPTTSHR
SCHEMBL24899569 0.93 KDM4E (0.34) ALDH1A1KDM4EPOLBMAPTTSHR
SCHEMBL25975701 0.93 ALDH1A1 (0.32) ALDH1A1KDM4EPOLBMAPTTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230189645-A1 ORGANIC LIGHT-EMITTING DEVICE, MANUFACTURING METHOD THEREFOR, AND COMPOSITION FOR ORGANIC MATERIAL LAYER OF ORGANIC LIGHT-EMITTING DEVICE LT MATERIALS CO., LTD. (KR) 2023-06-15 — — US disclosed
US-20230189645-A1 ORGANIC LIGHT-EMITTING DEVICE, MANUFACTURING METHOD THEREFOR, AND COMPOSITION FOR ORGANIC MATERIAL LAYER OF ORGANIC LIGHT-EMITTING DEVICE LT MATERIALS CO., LTD. (KR) 2023-06-15 — — US disclosed
US-20230128360-A1 HETEROCYCLIC COMPOUND, ORGANIC LIGHT EMITTING DEVICE COMPRISING SAME, COMPOSITION FOR ORGANIC LAYER OF ORGANIC LIGHT EMITTING DEVICE LT MATERIALS CO., LTD. (KR) 2023-04-27 — — US disclosed
WO-2020122576-A1 HETEROCYCLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME, METHOD FOR MANUFACTURING SAME, AND COMPOSITION FOR ORGANIC MATERIAL LAYER 엘티소재주식회사 2020-06-18 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230128360-A1 HETEROCYCLIC COMPOUND, ORGANIC LIGHT EMITTING DEVICE COMPRISING SAME, COMPOSITION FOR ORGANIC LAYER OF ORGANIC LIGHT EMITTING DEVICE CRY1, ORC3, ODC1 ALDH1A1 27/4885KDM4E 3080/4885POLB 2703/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.