Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.54 |
| ▸ | THRB | P10828 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | ILK | Q13418 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20267448 | 0.87 | MAPT (0.50) | MAPTTHRBALDH1A1POLBLMNA | |
| Ammonia Solution, Strong SCHEMBL27865864 | 0.84 | MAPT (0.42) | MAPTTHRBALDH1A1POLBTSHR | |
| SCHEMBL27969503 | 0.81 | TSHR (0.46) | MAPTALDH1A1POLBTSHRHPGD | |
| SCHEMBL31299616 | 0.80 | TSHR (0.53) | MAPTALDH1A1POLBTSHRHPGD | |
| SCHEMBL6216511 | 0.80 | MAPT (0.57) | MAPTTHRBALDH1A1POLBLMNA | |
| SCHEMBL28812803 | 0.79 | TSHR (0.44) | MAPTALDH1A1POLBTSHRHPGD | |
| SCHEMBL4950787 | 0.79 | TSHR (0.44) | MAPTALDH1A1POLBTSHRHPGD | |
| SCHEMBL1434485 | 0.79 | TSHR (0.44) | MAPTALDH1A1POLBTSHRHPGD | |
| SCHEMBL22263170 | 0.79 | TSHR (0.44) | MAPTALDH1A1POLBTSHRHPGD | |
| SCHEMBL6962972 | 0.78 | MAPT (0.56) | MAPTTHRBALDH1A1POLBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 62 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116768796-A | Novel pyrazole-3-carboxamide derivative and preparation method and application thereof | 河北农业大学 | 2023-09-19 | — | — | CN | claimed |
| US-20190031627-A1 | A KIND OF ISOTHIAZOLE OXIME ETHER-CONTAINING STROBILURIN DERIVATIVES AND ITS PREPARATION METHODS AND APPLICATION | NANKAI UNIVERSITY (CN) | 2019-01-31 | — | — | US | claimed |
| US-7785759-B2 | Thiadiazole containing charge transport layer photoconductors | XEROX CORPORATION (US) | 2010-08-31 | — | — | US | claimed |
| US-20090246667-A1 | THIADIAZOLE CONTAINING CHARGE TRANSPORT LAYER PHOTOCONDUCTORS | XEROX CORPORATION (US) | 2009-10-01 | — | — | US | claimed |
| US-20090246666-A1 | THIADIAZOLE CONTAINING PHOTOCONDUCTORS | XEROX CORPORATION (US) | 2009-10-01 | — | — | US | claimed |
| CN-119080854-A | Cytidine nucleoside compound based on glycine, preparation method and application thereof, and bactericidal and antiviral composition | 沈阳农业大学 | 2024-12-06 | — | — | CN | disclosed |
| CN-113480466-B | Indole substituted amide compound and preparation method and application thereof | 厦门大学 | 2024-09-06 | — | — | CN | disclosed |
| CN-113929695-B | Sulfimide psoralen derivatives, and preparation method and application thereof | 南开大学 | 2024-06-07 | — | — | CN | disclosed |
| CN-118126033-A | Method for synthesizing methyl thioluramine by one step through 4-methyl-1, 2, 3-thiadiazole-5-formate | 利尔化学股份有限公司 | 2024-06-04 | — | — | CN | disclosed |
| CN-113929697-B | 1,3, 4-Oxadiazole psoralen derivatives, and preparation method and application thereof | 南开大学 | 2024-05-14 | — | — | CN | disclosed |
| CN-113929696-B | Acyl thiourea psoralen derivatives, and preparation method and application thereof | 南开大学 | 2024-05-14 | — | — | CN | disclosed |
| CN-117430584-A | Novel pyrazole-pyridine derivatives, and preparation method and application thereof | 河北农业大学 | 2024-01-23 | — | — | CN | disclosed |
| EP-0930305-A1 | 1,2,3-THIADIAZOLE DERIVATIVES AND SALTS THEREOF, DISEASE CONTROLLING AGENTS FOR AGRICULTURAL AND HORTICULTURAL USE, AND METHOD FOR THE USE THEREOF | Nihon Nohyaku Co., Ltd. (JP) | 1999-07-21 | — | — | EP | disclosed |
| EP-0667868-A1 | NEW CEPHEM COMPOUNDS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1995-08-23 | — | — | EP | disclosed |
| WO-1995007283-A1 | NEW CEPHEM COMPOUNDS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1995-03-16 | — | — | WO | disclosed |
| EP-0154132-B1 | 6-ALKYLIDENE PENEMS, THEIR PREPARATION AND USE, AND INTERMEDIATES | BEECHAM GROUP PLC (GB) | 1992-01-08 | — | — | EP | disclosed |
| US-4798828-A | LACTAMASE INHIBITORS | BEECHAM GROUP P.L.C. (GB) | 1989-01-17 | — | — | US | disclosed |
| EP-0154132-A1 | 6-Alkylidene penems, their preparation and use, and intermediates | BEECHAM GROUP PLC (GB) | 1985-09-11 | — | — | EP | disclosed |
| US-4340742-A | Process for making 5-mercapto-1,2,3-triazoles | SCHERING AG (DE) | 1982-07-20 | — | — | US | disclosed |
| US-4177054-A | PREEMERGENT AND POSTEMERGENT | SCHERING AKTIENGESELLSCHAFT (DE) | 1979-12-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190031627-A1 | A KIND OF ISOTHIAZOLE OXIME ETHER-CONTAINING STROBILURIN DERIVATIVES AND ITS PREPARATION METHODS AND APPLICATION | STS, CDV3, SALL4 | MAPT 2178/4885THRB 3549/4885ALDH1A1 1557/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.