SCHEMBL4950787

SCHEMBL4950787

CCOC(=O)c1snnc1CCl

nearest known ligand 0.49

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.44
ALDH1A1 P00352 8/20 0.41
CYP1A2 P05177 1/20 0.41
MAPT P10636 5/20 0.40
SMN1; SMN2 Q16637 2/20 0.40
LMNA P02545 2/20 0.40
ILK Q13418 1/20 0.40
KDM4E B2RXH2 5/20 0.39
GAA P10253 2/20 0.38
HSD17B10 Q99714 2/20 0.38
RAB9A P51151 2/20 0.38
KMT2A Q03164 1/20 0.38
NPC1 O15118 1/20 0.38
MC4R P32245 1/20 0.38
HPGD P15428 3/20 0.38
POLB P06746 1/20 0.38
HTT P42858 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1434485 0.83 TSHR (0.44) TSHRALDH1A1CYP1A2MAPTLMNA
SCHEMBL22263170 0.83 TSHR (0.44) TSHRALDH1A1CYP1A2MAPTLMNA
SCHEMBL28812803 0.83 TSHR (0.44) TSHRALDH1A1CYP1A2MAPTLMNA
SCHEMBL2211256 0.79 MAPT (0.54) TSHRALDH1A1CYP1A2MAPTLMNA
SCHEMBL27969503 0.76 TSHR (0.46) TSHRALDH1A1CYP1A2MAPTSMN1; SMN2
SCHEMBL31299616 0.75 TSHR (0.53) TSHRALDH1A1CYP1A2MAPTLMNA
SCHEMBL4954406 0.72 MAPT (0.44) TSHRALDH1A1MAPTSMN1; SMN2LMNA
SCHEMBL2873389 0.71 ALDH1A1 (0.48) TSHRALDH1A1CYP1A2MAPTSMN1; SMN2
SCHEMBL31299652 0.71 TSHR (0.49) TSHRALDH1A1CYP1A2MAPTSMN1; SMN2
SCHEMBL9296047 0.69 TSHR (0.58) TSHRALDH1A1CYP1A2MAPTSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1915907-A2 An agricultural and horticultural disease controller Nihon Nohyaku Co., Ltd. (JP) 2008-04-30 EP disclosed
EP-1688041-A1 An agricultural and horticultural disease controller and a method for controlling the diseases Nihon Nohyaku Co., Ltd. (JP) 2006-08-09 EP disclosed
EP-0824317-B1 AN AGRICULTURAL AND HORTICULTURAL DISEASE CONTROLLER AND A METHOD FOR CONTROLLING THE DISEASES NIHON NOHYAKU CO LTD (JP) 2004-10-13 EP disclosed
EP-1413199-A1 An agricultural and horticultural disease controller and a method for controlling the diseases Nihon Nohyaku Co., Ltd. (JP) 2004-04-28 EP disclosed
US-6521649-B1 1,2,3-thiadiazole derivatives; expanding spectrum of controllable diseases and period of time when effective applications are possible; reducing dosage NIHON NOHAYKU CO., LTD. (JP) 2003-02-18 US disclosed
US-6166054-A Agricultural and horticultural disease controller and a method for controlling the diseases NIHON NOHYAKU CO., LTD. (JP) 2000-12-26 US disclosed
EP-0824317-A2 AN AGRICULTURAL AND HORTICULTURAL DISEASE CONTROLLER AND A METHOD FOR CONTROLLING THE DISEASES Nihon Nohyaku Co., Ltd. (JP) 1998-02-25 EP disclosed
WO-1996029871-A2 AN AGRICULTURAL AND HORTICULTURAL DISEASE CONTROLLER AND A METHOD FOR CONTROLLING THE DISEASES NIHON NOHYAKU CO., LTD. (JP) 1996-10-03 WO disclosed
US-4732977-A BACTERICIDES BRISTOL MYERS COMPANY (US) 1988-03-22 US disclosed