Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.56 |
| ▸ | THRB | P10828 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2211256 | 0.78 | MAPT (0.54) | MAPTTHRBPOLBLMNAALDH1A1 | |
| SCHEMBL4950288 | 0.77 | MAPT (0.55) | MAPTTHRBPOLBLMNAALDH1A1 | |
| SCHEMBL20267448 | 0.74 | MAPT (0.50) | MAPTTHRBPOLBLMNAALDH1A1 | |
| SCHEMBL452517 | 0.74 | — | — | |
| SCHEMBL7662839 | 0.73 | MAPT (0.49) | MAPTTHRBPOLBLMNAALDH1A1 | |
| SCHEMBL4779258 | 0.72 | — | — | |
| Hydrochloric Acid SCHEMBL6602988 | 0.72 | LMNA (0.51) | MAPTTHRBPOLBLMNAALDH1A1 | |
| SCHEMBL13545146 | 0.69 | MAPT (0.45) | MAPTTHRBPOLBLMNAALDH1A1 | |
| SCHEMBL13543211 | 0.69 | ALDH1A1 (0.45) | MAPTTHRBPOLBLMNAALDH1A1 | |
| SCHEMBL12292649 | 0.69 | LMNA (0.57) | MAPTPOLBLMNAALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1329160-A2 | 4-ACYLAMINOPYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-07-23 | — | — | EP | disclosed |