Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | GFER | P55789 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 4/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | KDM5A | P29375 | 1/20 | 0.35 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | UBE2N | P61088 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.34 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19329852 | 0.93 | MAPT (0.43) | KDM4EMAPTGFERNPC1RAB9A | |
| SCHEMBL24906160 | 0.85 | KDM4E (0.50) | KDM4EMAPTGFERNPC1RAB9A | |
| SCHEMBL20100550 | 0.79 | RAB9A (0.53) | KDM4EMAPTNPC1RAB9AALDH1A1 | |
| SCHEMBL1465598 | 0.79 | CYP2A6 (0.52) | KDM4EMAPTGFERNPC1RAB9A | |
| SCHEMBL3640169 | 0.77 | AOC3 (0.44) | KDM4EMAPTNPC1RAB9AALDH1A1 | |
| SCHEMBL17540810 | 0.76 | METAP2 (0.41) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL10441226 | 0.75 | AOC3 (0.42) | KDM4ENPC1RAB9AALDH1A1CYP2A6 | |
| SCHEMBL30864294 | 0.74 | HRH4 (0.43) | HRH4 | |
| SCHEMBL22091286 | 0.70 | MAPT (0.94) | KDM4EMAPTGFERNPC1RAB9A | |
| SCHEMBL20740536 | 0.69 | CYP19A1 (0.44) | MAPTNPC1ALDH1A1HRH4MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020120576-A1 | p38α AUTOPHOSPHORYLATION INHIBITORS | FUNDACIÓ INSTITUT DE RECERCA BIOMÈDICA (IRB BARCELONA) (ES) | 2020-06-18 | — | — | WO | disclosed |