Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.43 |
| ▸ | CHRNB2 | P17787 | 3/20 | 0.40 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.40 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.40 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.40 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.40 |
| ▸ | PARP1 | P09874 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13634946 | 0.81 | CHRNB2 (0.50) | CHRNB2CHRNA4CHRNB4CHRNA3CHRNA7 | |
| SCHEMBL30205030 | 0.78 | HRH4 (0.49) | HRH4CHRNB2CHRNA4CHRNB4CHRNA3 | |
| SCHEMBL22112660 | 0.74 | KDM4E (0.51) | HRH4 | |
| SCHEMBL31753410 | 0.74 | CHRNA7 (0.49) | HRH4CHRNB2CHRNA4CHRNB4CHRNA3 | |
| SCHEMBL30864313 | 0.74 | CHRNA7 (0.49) | HRH4CHRNB2CHRNA4CHRNB4CHRNA3 | |
| SCHEMBL19329852 | 0.74 | MAPT (0.43) | HRH4CHRNB2CHRNA4PARP1 | |
| SCHEMBL31746690 | 0.73 | CHRNB2 (0.37) | CHRNB2CHRNA4 | |
| SCHEMBL31746382 | 0.73 | CHRNB2 (0.37) | CHRNB2CHRNA4 | |
| SCHEMBL30204284 | 0.73 | PARP1 (0.50) | PARP1 | |
| Hydrochloric Acid SCHEMBL31746350 | 0.72 | CCNT1 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117858877-A | C-linked inhibitors of ENL/AF9 YEATS | 桥梁药品有限公司 | 2024-04-09 | — | — | CN | disclosed |