SCHEMBL22114508

SCHEMBL22114508

C=C/C=C\C=C(/C)c1cc(-c2ccccc2)cc(-c2nc(-c3cccc(-c4ccccn4)c3)nc(-c3cccc(-c4ccccn4)c3)n2)c1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KAT6A Q92794 1/20 0.35
▸ GRM5 P41594 5/20 0.35
▸ KDM4E B2RXH2 3/20 0.34
▸ TDP1 Q9NUW8 1/20 0.34
▸ RAB9A P51151 4/20 0.34
▸ SMN1; SMN2 Q16637 4/20 0.34
▸ LMNA P02545 3/20 0.34
▸ MAPT P10636 2/20 0.34
▸ TP53 P04637 2/20 0.34
▸ PKM P14618 2/20 0.34
▸ ALDH1A1 P00352 1/20 0.34
▸ HPGD P15428 1/20 0.34
▸ TSHR P16473 1/20 0.34
▸ KLF5 Q13887 1/20 0.34
▸ HSD17B10 Q99714 1/20 0.34
▸ TLR4 O00206 1/20 0.33
▸ TLR2 O60603 1/20 0.33
▸ NPC1 O15118 3/20 0.33
▸ PIK3CA P42336 1/20 0.33
▸ PIK3CB P42338 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12948982 0.87 TLR4 (0.39) KAT6AGRM5KDM4ETDP1RAB9A
SCHEMBL24642252 0.86 KMO (0.41) GRM5KDM4ETDP1LMNAMAPT
SCHEMBL24626925 0.83 KDM4E (0.37) KDM4ETDP1RAB9ASMN1; SMN2LMNA
SCHEMBL24627008 0.81 KDM4E (0.34) KDM4ERAB9ASMN1; SMN2LMNAMAPT
SCHEMBL17932826 0.80 KDM4E (0.52) KAT6AGRM5KDM4ETDP1RAB9A
SCHEMBL25662211 0.79 KDM4E (0.50) KAT6AGRM5KDM4ETDP1RAB9A
SCHEMBL17932281 0.79 KDM4E (0.50) KAT6AGRM5KDM4ETDP1RAB9A
SCHEMBL19200791 0.79 GRM5 (0.38) KAT6AGRM5RAB9ALMNAMAPT
SCHEMBL24626890 0.78 GRM5 (0.36) GRM5KDM4ERAB9ANPC1PIK3CA
SCHEMBL24608650 0.78 SGK1 (0.31) —

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230284471-A1 LIGHT-EMITTING DEVICE AND ELECTRONIC APPARATUS INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2023-09-07 — — US disclosed
US-11690287-B2 Organic light-emitting device and display apparatus including the same SAMSUNG DISPLAY CO., LTD. (KR) 2023-06-27 — — US disclosed
US-20200203621-A1 ORGANIC LIGHT-EMITTING DEVICE AND DISPLAY APPARATUS INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2020-06-25 — — US disclosed
US-20200194694-A1 ORGANOMETALLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2020-06-18 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11690287-B2 Organic light-emitting device and display apparatus including the same OR10J3, ALDH1A2, OCIAD1 KAT6A 4716/4885GRM5 2462/4885KDM4E 3054/4885
US-20200203621-A1 ORGANIC LIGHT-EMITTING DEVICE AND DISPLAY APPARATUS INCLUDING THE SAME OR10J3, ALDH1A2, OCIAD1 KAT6A 4716/4885GRM5 2462/4885KDM4E 3054/4885
US-20200194694-A1 ORGANOMETALLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME ORC3, OCIAD1, PPOX KAT6A 2552/4885GRM5 2163/4885KDM4E 2236/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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