Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNAI3 | P08754 | 2/20 | 0.40 |
| ▸ | GNAO1 | P09471 | 2/20 | 0.40 |
| ▸ | GNAI1 | P63096 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CHKA | P35790 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | NAMPT | P43490 | 1/20 | 0.33 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.32 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.32 |
| ▸ | P2RY12 | Q9H244 | 3/20 | 0.32 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.31 |
| ▸ | HRH2 | P25021 | 1/20 | 0.31 |
| ▸ | HRH1 | P35367 | 1/20 | 0.31 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22115337 | 0.95 | GNAI3 (0.43) | GNAI3GNAO1GNAI1LMNAPOLB | |
| SCHEMBL24234391 | 0.85 | LMNA (0.38) | GNAI3GNAO1GNAI1LMNAPOLB | |
| SCHEMBL22114846 | 0.79 | LMNA (0.42) | GNAI3GNAO1GNAI1LMNAPOLB | |
| SCHEMBL112600 | 0.79 | SMN1; SMN2 (0.56) | GNAI3GNAO1GNAI1LMNAPOLB | |
| SCHEMBL22407731 | 0.76 | SMN1; SMN2 (0.44) | LMNAPOLBSMN1; SMN2CA2CHKA | |
| SCHEMBL9123475 | 0.76 | LMNA (0.55) | GNAI3GNAO1GNAI1LMNAPOLB | |
| SCHEMBL27694189 | 0.76 | LMNA (0.55) | GNAI3GNAO1GNAI1LMNAPOLB | |
| SCHEMBL25424462 | 0.76 | LMNA (0.55) | GNAI3GNAO1GNAI1LMNAPOLB | |
| Hydrochloric Acid SCHEMBL22407717 | 0.75 | SMN1; SMN2 (0.43) | GNAI3GNAO1GNAI1LMNAPOLB | |
| SCHEMBL5667296 | 0.74 | LMNA (0.57) | GNAI3GNAO1GNAI1LMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020123836-A2 | HERBOXIDIENE SPLICING MODULATOR ANTIBODY-DRUG CONJUGATES AND METHODS OF USE | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2020-06-18 | — | — | WO | disclosed |