SCHEMBL5667296

SCHEMBL5667296

CCCCCOC(=O)N1CCNCC1

nearest known ligand 0.57

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.57
POLB P06746 1/20 0.57
SMN1; SMN2 Q16637 1/20 0.57
GBA2 Q9HCG7 1/20 0.44
GNAI3 P08754 4/20 0.43
GNAO1 P09471 4/20 0.43
GNAI1 P63096 4/20 0.43
NAAA Q02083 1/20 0.43
HRH2 P25021 1/20 0.42
HRH1 P35367 1/20 0.42
PLA2G2A P14555 2/20 0.41
EPHX1 P07099 1/20 0.41
P2RY12 Q9H244 3/20 0.40
TSHR P16473 2/20 0.40
ACHE P22303 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9123475 0.98 LMNA (0.55) LMNAPOLBSMN1; SMN2GBA2GNAI3
SCHEMBL27694189 0.98 LMNA (0.55) LMNAPOLBSMN1; SMN2GBA2GNAI3
SCHEMBL17017 0.95 POLB (0.63) LMNAPOLBSMN1; SMN2GBA2GNAI3
SCHEMBL18760256 0.95 POLB (0.63) LMNAPOLBSMN1; SMN2GBA2GNAI3
SCHEMBL5820669 0.95 POLB (0.63) LMNAPOLBSMN1; SMN2GBA2GNAI3
Potassium SCHEMBL30906131 0.93 POLB (0.61) LMNAPOLBSMN1; SMN2GBA2GNAI3
SCHEMBL4082478 0.93 POLB (0.61) LMNAPOLBSMN1; SMN2GBA2GNAI3
Hydrochloric Acid SCHEMBL1111003 0.93 POLB (0.61) LMNAPOLBSMN1; SMN2GBA2GNAI3
SCHEMBL31093994 0.91 LMNA (0.49) LMNAPOLBSMN1; SMN2GBA2GNAI3
SCHEMBL112600 0.89 SMN1; SMN2 (0.56) LMNAPOLBSMN1; SMN2GBA2GNAI3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3409718-B1 MODIFIER AND MODIFIED CONJUGATED DIENE-BASED POLYMER CONTAINING FUNCTIONAL GROUP DERIVED THEREFROM LG CHEMICAL LTD (KR) 2020-08-19 EP disclosed
US-10730984-B2 Modifier and modified conjugated diene-based polymer including functional group derived therefrom LG CHEM, LTD. (KR) 2020-08-04 US disclosed
CN-108884271-B Modifier and modified conjugated diene-based polymer containing functional group derived therefrom 株式会社LG化学 2020-07-10 CN disclosed
EP-3409718-A1 MODIFIER AND MODIFIED CONJUGATED DIENE-BASED POLYMER CONTAINING FUNCTIONAL GROUP DERIVED THEREFROM LG Chem, Ltd. (KR) 2018-12-05 EP disclosed
US-7279470-B2 Compounds and uses thereof for decreasing activity of hormone-sensitive lipase NOVO NORDISK A/S (DK) 2007-10-09 US disclosed
US-7067517-B2 Use of compounds for decreasing activity of hormone-sensitive lipase NERO NORDISK A/S (DK) 2006-06-27 US disclosed
EP-1458375-A2 COMPOSITIONS FOR DECREASING ACTIVITY OF HORMONE-SENSITIVE LIPASE NOVO NORDISK A/S (DK) 2004-09-22 EP disclosed
EP-1458374-A2 COMPOUNDS AND USES THEREOF FOR DECREASING ACTIVITY OF HORMONE-SENSITIVE LIPASE NOVO NORDISK A/S (DK) 2004-09-22 EP disclosed
US-20030166644-A1 Compounds and uses thereof for decreasing activity of hormone-sensitive lipase NOVO NORDISK A/S (DK) 2003-09-04 US disclosed
US-20030166690-A1 Use of compounds for decreasing activity of hormone-sensitive NOVO NORDISK A/S (DK) 2003-09-04 US disclosed
WO-2003051841-A2 COMPOUNDS AND USES THEREOF FOR DECREASING ACTIVITY OF HORMONE-SENSITIVE LIPASE NOVO NORDISK A/S (DK) 2003-06-26 WO disclosed
WO-2003051842-A2 COMPOSITIONS DECREASING ACTIVITY OF HORMONE-SENSITIVE LIPASE NOVO NORDISK A/S (DK) 2003-06-26 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030166644-A1 Compounds and uses thereof for decreasing activity of hormone-sensitive lipase LIPE, PNLIP, LPL LMNA 1410/4885POLB 3606/4885SMN1; SMN2 4233/4885
US-10730984-B2 Modifier and modified conjugated diene-based polymer including functional group derived therefrom WASF2, ITGAM, ORMDL3 LMNA 2448/4885POLB 4255/4885SMN1; SMN2 4376/4885
US-20030166690-A1 Use of compounds for decreasing activity of hormone-sensitive LIPE, PNLIP, LPL LMNA 2068/4885POLB 2734/4885SMN1; SMN2 4133/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.