Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | SRC | P12931 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.41 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11813692 | 0.83 | TSHR (0.52) | TSHRTRPA1TDP1L3MBTL1CYP2D6 | |
| SCHEMBL1019171 | 0.83 | TSHR (0.52) | TSHRTRPA1TDP1L3MBTL1CYP2D6 | |
| Ammonia Solution, Strong SCHEMBL38661532 | 0.81 | TSHR (0.50) | TSHRTRPA1TDP1L3MBTL1CYP2D6 | |
| SCHEMBL6960576 | 0.81 | TSHR (0.50) | TSHRTRPA1TDP1L3MBTL1CYP2D6 | |
| SCHEMBL10432296 | 0.79 | TSHR (0.48) | TSHRTRPA1TDP1L3MBTL1CYP2D6 | |
| SCHEMBL2927032 | 0.79 | TSHR (0.48) | TSHRTRPA1TDP1L3MBTL1CYP2D6 | |
| SCHEMBL2771881 | 0.79 | TSHR (0.48) | TSHRTRPA1TDP1L3MBTL1CYP2D6 | |
| SCHEMBL1720075 | 0.79 | ALDH1A1 (0.49) | TSHRTRPA1TDP1L3MBTL1CYP2D6 | |
| SCHEMBL10439400 | 0.79 | LMNA (0.44) | TSHRTRPA1TDP1L3MBTL1CYP2D6 | |
| SCHEMBL5505530 | 0.78 | L3MBTL1 (0.61) | TSHRTRPA1TDP1L3MBTL1CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2348120-B1 | Enzymatic reduction of 1-phenylpropanone and derivatives thereof | Universität Wien (AT) | 2014-06-11 | — | — | EP | disclosed |
| EP-2348120-A1 | Enzymatic reduction of 1-phenylpropanone and derivatives thereof | Universität Wien (AT) | 2011-07-27 | — | — | EP | disclosed |
| US-4005074-A | Process for cleaving an imido side chain from penicillins and cephalosporins | ELI LILLY AND COMPANY (US) | 1977-01-25 | — | — | US | disclosed |
| US-4001239-A | CEPHALOSPORIN CLEAVAGE PROCESS | ELI LILLY AND COMPANY (US) | 1977-01-04 | — | — | US | disclosed |
| US-3994888-A | Cephalosporin cleavage process | ELI LILLY AND COMPANY (US) | 1976-11-30 | — | — | US | disclosed |