SCHEMBL221163

SCHEMBL221163

CN(C)c1ccc(C2(c3ccc(N(C)C)cc3)OC(=O)c3cc(Cl)ccc32)cc1

nearest known ligand 0.81

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 3/20 0.81
ALDH1A1 P00352 2/20 0.81
CYP3A4 P08684 2/20 0.81
HSD17B10 Q99714 2/20 0.81
HPGD P15428 1/20 0.81
HIF1A Q16665 1/20 0.81
MEN1 O00255 4/20 0.73
KMT2A Q03164 4/20 0.73
CFTR P13569 1/20 0.44
GOPC Q9HD26 1/20 0.44
LMNA P02545 4/20 0.43
MAPT P10636 3/20 0.43
SMN1; SMN2 Q16637 3/20 0.43
POLB P06746 2/20 0.43
TYMS P04818 2/20 0.43
TP53 P04637 2/20 0.43
TSHR P16473 2/20 0.43
ESR1 P03372 1/20 0.43
ALOX15 P16050 1/20 0.43
ESR2 Q92731 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18143522 0.90 ALDH1A1 (1.00) TDP1ALDH1A1CYP3A4HSD17B10HPGD
SCHEMBL27188 0.90 ALDH1A1 (1.00) TDP1ALDH1A1CYP3A4HSD17B10HPGD
SCHEMBL7162246 0.87 TDP1 (0.73) TDP1ALDH1A1CYP3A4HSD17B10HPGD
SCHEMBL11299095 0.86 TDP1 (0.72) TDP1ALDH1A1CYP3A4HSD17B10HPGD
SCHEMBL12152338 0.86 ALDH1A1 (0.81) TDP1ALDH1A1CYP3A4HSD17B10HPGD
SCHEMBL5282818 0.85 TDP1 (0.75) TDP1ALDH1A1CYP3A4HSD17B10HPGD
SCHEMBL10693177 0.85 TDP1 (0.80) TDP1ALDH1A1CYP3A4HSD17B10HPGD
SCHEMBL1892014 0.85 ALDH1A1 (0.59) TDP1ALDH1A1CYP3A4HSD17B10HPGD
SCHEMBL29441219 0.84 TDP1 (0.79) TDP1ALDH1A1CYP3A4HSD17B10HPGD
SCHEMBL3398340 0.84 MEN1 (1.00) TDP1ALDH1A1CYP3A4HSD17B10HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 557 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11435293-B2 Dual-function heat indicator and method of manufacture TEMPTIME CORPORATION (US) 2022-09-06 US claimed
US-20180321159-A1 DUAL-FUNCTION HEAT INDICATOR AND METHOD OF MANUFACTURE TEMPTIME CORPORATION (US) 2018-11-08 US claimed
US-10031086-B2 Dual function heat indicator and method of manufacture TEMPTIME CORPORATION (US) 2018-07-24 US claimed
US-20160313253-A1 DUAL-FUNCTION HEAT INDICATOR AND METHOD OF MANUFACTURE ZEBRA TECHNOLOGIES CORPORATION 2016-10-27 US claimed
US-20160069812-A1 DUAL FUNCTION HEAT INDICATOR AND METHOD OF MANUFACTURE ZEBRA TECHNOLOGIES CORPORATION 2016-03-10 US claimed
EP-2847563-A2 DUAL-FUNCTION HEAT INDICATOR AND METHOD OF MANUFACTURE Temptime Corporation (US) 2015-03-18 EP claimed
US-20140044609-A1 DUAL-FUNCTION HEAT INDICATOR AND METHOD OF MANUFACTURE TEMPTIME CORPORATION (US) 2014-02-13 US claimed
WO-2013170273-A2 DUAL-FUNCTION HEAT INDICATOR AND METHOD OF MANUFACTURE TEMPTIME CORPORATION (US) 2013-11-14 WO claimed
US-4845072-A COLORING LAYER COMPRISING A LEUCO DYE, A COLOR DEVELOPER AND A VINYL ETHER COMPOUND RICOH COMPANY, LTD. (JP) 1989-07-04 US claimed
US-4816501-A HEATING WITH EPOXY GROUP MODIFIED POLYVINYL ALCOHOL DENKI KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1989-03-28 US claimed
US-4638340-A PROTECTIVE AND DECOLORING INTERMEDIATE LAYERS TO PRODUCE SEPARATE AND DISTINCT COLOR RICOH COMPANY, LTD. (JP) 1987-01-20 US claimed
US-12623478-B2 Thermosensitive recording layer forming liquid, thermosensitive recording medium and production method thereof, and image recording method RICOH COMPANY, LTD. (JP) 2026-05-12 US disclosed
EP-4022391-B1 HEAT SENSITIVE RECORDING MATERIAL WITH NON-PHENOLIC COLOR DEVELOPERS SOLENIS TECHNOLOGIES CAYMAN LP (KY) 2026-03-04 EP disclosed
EP-4676749-A1 THERMOSENSITIVE RECORDING MEDIUM, METHOD FOR PRODUCING THERMOSENSITIVE RECORDING MEDIUM, AND ARTICLE COMPRISING THE THERMOSENSITIVE RECORDING MEDIUM Ricoh Company, Ltd. (JP) 2026-01-14 EP disclosed
US-12422418-B2 Activatable print medium ZEBRA TECHNOLOGIES CORPORATION (US) 2025-09-23 US disclosed
US-4251593-A Heat-sensitive recording sheet RICOH COMPANY, LTD. (JP) 1981-02-17 US disclosed
US-4247595-A CHROMOGEN, DEVELOPER, BINDER, HEXAGONAL THIN PLATE KAOLIN FILLER RICOH CO., LTD. (JP) 1981-01-27 US disclosed
EP-0012587-A1 Thermo-sensitive multi-color recording material and process for preparation thereof Ricoh Company, Ltd (JP) 1980-06-25 EP disclosed
EP-0008205-A1 Thermosensitive recording material Ricoh Company, Ltd (JP) 1980-02-20 EP disclosed
US-4180405-A COLOR-FORMING LACTONES OR SPIROPYRANS WITH CYCLIC POLYKETO COLOR PRECURSOR GRAPHIC CONTROLS CORPORATION (US) 1979-12-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12623478-B2 Thermosensitive recording layer forming liquid, thermosensitive recording medium and production method thereof, and image recording method TRPA1, ASIC1, LRBA TDP1 2624/4885ALDH1A1 431/4885CYP3A4 2156/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.